Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934569 | 0.82 | TSHR (0.58) | TSHRKCNH2ALDH1A1MAOBMAPT | |
| SCHEMBL9165352 | 0.81 | TSHR (0.55) | TSHRKCNH2EPHX1 | |
| SCHEMBL11308396 | 0.81 | TSHR (0.55) | TSHRKCNH2EPHX1 | |
| SCHEMBL8727026 | 0.81 | TSHR (0.55) | TSHRKCNH2EPHX1 | |
| SCHEMBL3656180 | 0.81 | TSHR (0.62) | TSHRKCNH2ALDH1A1 | |
| SCHEMBL9574244 | 0.80 | RAB9A (0.42) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL17466050 | 0.80 | MAPT (0.60) | KCNH2ALDH1A1MAOBMAPTL3MBTL1 | |
| SCHEMBL1312040 | 0.80 | TSHR (0.47) | TSHRKCNH2EPHX1 | |
| SCHEMBL9574159 | 0.80 | ALDH1A1 (0.58) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8855273 | 0.79 | TSHR (0.61) | TSHRKCNH2ALDH1A1MAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |