Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GLS | O94925 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3213661 | 0.81 | CASP3 (0.49) | GAAMEN1KMT2ACASP3GLS | |
| SCHEMBL10488503 | 0.79 | CASP3 (0.65) | RAB9AGAAMAPTKMT2ACASP3 | |
| SCHEMBL29018590 | 0.79 | GAA (0.56) | RAB9AGAAMAPTNPC1MEN1 | |
| SCHEMBL53287 | 0.77 | BCHE (0.63) | RAB9AMAPTNPC1CASP3GLS | |
| SCHEMBL30434337 | 0.77 | BCHE (0.63) | RAB9AMAPTNPC1CASP3GLS | |
| SCHEMBL3242823 | 0.76 | MAPT (0.57) | RAB9AGAAMAPTNPC1MEN1 | |
| SCHEMBL4656546 | 0.76 | GAA (0.50) | RAB9AGAAMAPTNPC1MEN1 | |
| SCHEMBL6699936 | 0.76 | GLS (0.71) | RAB9AMAPTNPC1CASP3GLS | |
| SCHEMBL1429821 | 0.75 | CASP3 (0.65) | RAB9AGAAMAPTKMT2ACASP3 | |
| SCHEMBL24618276 | 0.75 | MAPT (0.49) | RAB9AGAAMAPTNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873254-A | ADRENERGIC BLOCKING AGENTS OR CALCIUM CHANNEL BLOCKERS; HYPOTENSIVE AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-10-10 | — | — | US | disclosed |