Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GLS | O94925 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13979654 | 0.90 | GAA (0.42) | GAAMAPTRAB9AMEN1NPC1 | |
| SCHEMBL30601267 | 0.83 | RXFP1 (0.51) | GAAMEN1KMT2ACASP3GLS | |
| SCHEMBL13979631 | 0.80 | MAPT (0.45) | GAAMAPTRAB9AMEN1NPC1 | |
| SCHEMBL4887026 | 0.78 | MAPT (0.43) | GAAMAPTRAB9AMEN1NPC1 | |
| SCHEMBL13979638 | 0.78 | MAPT (0.43) | GAAMAPTRAB9AMEN1NPC1 | |
| SCHEMBL29018590 | 0.76 | GAA (0.56) | GAAMAPTRAB9AMEN1NPC1 | |
| SCHEMBL10488389 | 0.76 | RAB9A (0.53) | GAAMAPTRAB9AMEN1NPC1 | |
| SCHEMBL3931444 | 0.73 | CASP3 (0.61) | GAAMAPTRAB9AKMT2ACASP3 | |
| SCHEMBL3242823 | 0.73 | MAPT (0.57) | GAAMAPTRAB9AMEN1NPC1 | |
| SCHEMBL6699936 | 0.73 | GLS (0.71) | MAPTRAB9ANPC1CASP3GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706113-B1 | A PROCESS FOR THE PREPARATION OF 4-(2-DIPROPYLAMINOETHYL)-1,3-DIHYDRO-2H-INDOL-2-ONE HYDROCHLORIDE | USV LTD (IN) | 2008-12-10 | — | — | EP | disclosed |
| EP-1706113-B1 | A PROCESS FOR THE PREPARATION OF 4-(2-DIPROPYLAMINOETHYL)-1,3-DIHYDRO-2H-INDOL-2-ONE HYDROCHLORIDE | USV LTD (IN) | 2008-12-10 | — | — | EP | disclosed |
| US-7378439-B2 | Process for the preparation of 4-(2-dipropylaminoethyl)-1,3-dihydro-2H-indol-2-one hydrochloride | USV, LTD. (IN) | 2008-05-27 | — | — | US | disclosed |
| WO-2007048472-A1 | HAIR TREATMENT METHOD THAT PROVIDES IMPROVED HAIR CARE AND AGENT FOR CARRYING OUT SAID METHOD | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-05-03 | — | — | WO | disclosed |
| CN-1909901-A | A process for the preparation of 4-(2-dipropylaminoethyl)-1,3-dihydro-2H-indol-2-one hydrochloride | USV LTD (IN) | 2007-02-07 | — | — | CN | disclosed |
| EP-1706113-A1 | A PROCESS FOR THE PREPARATION OF 4-(2-DIPROPYLAMINOETHYL)-1,3-DIHYDRO-2H-INDOL-2-ONE HYDROCHLORIDE | USV Limited (IN) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005067922-A1 | A PROCESS FOR THE PREPARATION OF 4-(2-DIPROPYLAMINOETHYL)-1,3-DIHYDRO-2H-INDOL-2-ONE HYDROCHLORIDE | USV LIMITED (IN) | 2005-07-28 | — | — | WO | disclosed |
| US-20050159605-A1 | Process for the preparation of 4-(2-dipropylaminoethyl)-1,3-dihydro-2H-indol-2-one hydrochloride | USV LIMITED (IN) | 2005-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159605-A1 | Process for the preparation of 4-(2-dipropylaminoethyl)-1,3-dihydro-2H-indol-2-one hydrochloride | PARK7, SNCA, TPH1 | GAA 1253/4885MAPT 95/4885RAB9A 302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.