Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | CASP6 | P55212 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22690198 | 0.88 | ALDH1A1 (0.48) | RAPGEF4TDP1ALDH1A1KDM4EPOLB | |
| SCHEMBL7720133 | 0.83 | RAPGEF4 (0.47) | RAPGEF4TDP1ALDH1A1KDM4EPOLB | |
| SCHEMBL11695199 | 0.80 | HSD17B10 (0.45) | RAPGEF4TDP1ALDH1A1KDM4EPOLB | |
| SCHEMBL157161 | 0.79 | RAPGEF4 (0.49) | RAPGEF4TDP1ALDH1A1KDM4EPOLB | |
| SCHEMBL11695007 | 0.78 | RAPGEF4 (0.43) | RAPGEF4TDP1ALDH1A1KDM4EPOLB | |
| SCHEMBL29399463 | 0.77 | RAPGEF4 (0.50) | RAPGEF4TDP1ALDH1A1KDM4EPOLB | |
| SCHEMBL29963180 | 0.77 | RAPGEF4 (0.50) | RAPGEF4TDP1ALDH1A1KDM4EPOLB | |
| SCHEMBL6427620 | 0.77 | RAPGEF4 (0.50) | RAPGEF4TDP1ALDH1A1KDM4EPOLB | |
| SCHEMBL9628291 | 0.77 | RAPGEF4 (0.50) | RAPGEF4TDP1ALDH1A1KDM4EPOLB | |
| SCHEMBL30839521 | 0.76 | RAPGEF4 (0.44) | RAPGEF4TDP1ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4864018-A | REACTIVE TRIAZINE-TYPE DYES HAVING PREFERENTIAL BINDING CAPACITY FOR BIOLOGICAL MOLECULES; PROTEIN AND ENZYMES ADSORBENTS AND PRECIPITATES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-09-05 | — | — | US | disclosed |
| EP-0209284-A2 | Anthraquinone derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-01-21 | — | — | EP | disclosed |