SCHEMBL7720133

SCHEMBL7720133

CNCc1ccc(N)cc1S(=O)(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.47
ALDH1A1 P00352 6/20 0.47
TDP1 Q9NUW8 4/20 0.47
GAA P10253 3/20 0.47
MAPT P10636 3/20 0.47
RECQL P46063 3/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
CASP6 P55212 3/20 0.47
KDM4E B2RXH2 2/20 0.47
POLB P06746 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
ELAVL1 Q15717 1/20 0.47
NSD2 O96028 2/20 0.45
APEX1 P27695 1/20 0.45
APOBEC3A P31941 1/20 0.45
APOBEC3G Q9HC16 1/20 0.45
HSD17B10 Q99714 6/20 0.43
NT5E P21589 3/20 0.40
TSHR P16473 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29399463 0.84 RAPGEF4 (0.50) RAPGEF4ALDH1A1TDP1GAAMAPT
SCHEMBL9628291 0.84 RAPGEF4 (0.50) RAPGEF4ALDH1A1TDP1GAAMAPT
SCHEMBL11701345 0.84 RAPGEF4 (0.45) RAPGEF4ALDH1A1TDP1GAAMAPT
SCHEMBL11695199 0.84 HSD17B10 (0.45) RAPGEF4ALDH1A1TDP1GAAMAPT
SCHEMBL10488690 0.83 RAPGEF4 (0.44) RAPGEF4ALDH1A1TDP1GAAMAPT
Ammonia Solution, Strong SCHEMBL7550166 0.82 RAPGEF4 (0.49) RAPGEF4ALDH1A1TDP1GAAMAPT
SCHEMBL157161 0.82 RAPGEF4 (0.49) RAPGEF4ALDH1A1TDP1GAAMAPT
SCHEMBL10507767 0.82 P2RY12 (0.41) RAPGEF4GAAMAPTL3MBTL1TSHR
SCHEMBL22690198 0.82 ALDH1A1 (0.48) RAPGEF4ALDH1A1TDP1GAAMAPT
SCHEMBL11695007 0.81 RAPGEF4 (0.43) RAPGEF4ALDH1A1TDP1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376656-B1 DISAZO DYES, TRIAZINE DYES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2002-04-23 US disclosed
EP-1097970-A2 Water-soluble monoazo compounds, process for their preparation and their use as dyestuffs DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2001-05-09 EP disclosed
EP-0774493-B1 Fiber-reactive azo dyestuffs, process for their preparation and use thereof DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-04-04 EP disclosed
EP-1075500-A1 WATER-SOLUBLE MONOAZO COMPOUNDS, METHOD FOR PRODUCING SAME AND THEIR USE AS DYES DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2001-02-14 EP disclosed
EP-0627471-B1 Reactive dyes BAYER AG (DE) 2000-08-23 EP disclosed
EP-0652262-B1 Reactive dyestuffs, their preparation and use BAYER AG (DE) 2000-07-12 EP disclosed
US-6025478-A HIGH REACTIVITY AND FIXING CAPACITY, GOOD LOW TEMPERATURE DYEING, GOOD COLOR INTENSITY, LIGHTFASTNESS, WASHFASTNESS BAYER AG (DE) 2000-02-15 US disclosed
WO-1999058612-A1 WATER-SOLUBLE MONOAZO COMPOUNDS, METHOD FOR PRODUCING SAME AND THEIR USE AS DYES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1999-11-18 WO disclosed
US-5760193-A FOR COTTON, WOOL, POLYAMIDES; HIGH COLOR STRENGTH, COLORFASTNESS DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1998-06-02 US disclosed
WO-1997025471-A1 METHOD OF PRODUCING COLOURED NATURAL OR SYNTHETIC SUBSTRATES AND SECONDARY TREATMENT OF SAID SUBSTRATES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1997-07-17 WO disclosed
EP-0652262-A1 Reactive dyestuffs, their preparation and use BAYER AG (DE) 1995-05-10 EP disclosed
EP-0627471-A1 Reactive dyes BAYER AG (DE) 1994-12-07 EP disclosed
EP-0012348-B1 A BINDING AGENT COMPRISING A POLYISOCYANATE COMPONENT AND A POLYHYDROXY COMPONENT FOR COATING MEANS APPLIED FROM AN AQUEOUS PHASE BAYER AG (DE) 1982-02-24 EP disclosed
US-4284544-A Process for the preparation of water-dispersible or water-soluble blocked polyisocyanates, the blocked polyisocyanates obtainable by this process and lacquer binders containing these blocked polyisocyanates as isocyanate component BAYER AKTIENGESELLSCHAFT (DE) 1981-08-18 US disclosed
EP-0012348-A1 A binding agent comprising a polyisocyanate component and a polyhydroxy component for coating means applied from an aqueous phase BAYER AG (DE) 1980-06-25 EP disclosed
US-4118382-A DYES FOR CELLULOSE, WOOL, SILK, POLYAMIDE, AND POLYURETHANE FIBERS BAYER AKTIENGESELLSCHAFT (DE) 1978-10-03 US disclosed
US-4052386-A REACTIVE PHTHALOCYANINE DYESTUFFS CONTAINING A FLUOROPYRIMIDINYL GROUP BAYER AKTIENGESELLSCHAFT (DT) 1977-10-04 US disclosed
US-4051134-A Reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-09-27 US disclosed
US-4007164-A FIBER-REACTIVE, CELLULOSE, WOOL BAYER AKTIENGESELLSCHAFT (DT) 1977-02-08 US disclosed
US-3988310-A FIBER-REACTIVE DYES; CELLULOSE BAYER AKTIENGESELLSCHAFT (DT) 1976-10-26 US disclosed