Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10489876 | 0.79 | RAB9A (0.50) | KMT2AMEN1ALDH1A1HPGDGAA | |
| SCHEMBL10489851 | 0.79 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1HPGDLMNA | |
| SCHEMBL10489739 | 0.79 | CLCN2 (0.45) | ALDH1A1HPGDFTOCLCN2KCNK3 | |
| SCHEMBL10489904 | 0.76 | RAB9A (0.60) | KMT2AMEN1ALDH1A1HPGDLMNA | |
| SCHEMBL10489678 | 0.76 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1HPGDGAA | |
| SCHEMBL10489988 | 0.76 | FAAH (0.46) | KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL10489688 | 0.74 | HPGD (0.48) | KMT2AMEN1ALDH1A1HPGDLMNA | |
| SCHEMBL10489991 | 0.73 | RAB9A (0.44) | KMT2AMEN1ALDH1A1HPGDGAA | |
| SCHEMBL10489681 | 0.72 | NPC1 (0.62) | KMT2AALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL10489848 | 0.72 | SMN1; SMN2 (0.56) | ALDH1A1HPGDLMNAGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873232-A | ARTHRITIS AND AUTOIMMUNE DISEASES | SYNTEX (US) | 1989-10-10 | — | — | US | disclosed |