Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GRK2 | P25098 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10489876 | 0.91 | RAB9A (0.50) | ALDH1A1GAARAB9ANPC1KMT2A | |
| SCHEMBL10489904 | 0.90 | RAB9A (0.60) | ALDH1A1GAASMN1; SMN2HTTTDP1 | |
| SCHEMBL10489991 | 0.86 | RAB9A (0.44) | ALDH1A1GAASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL10489739 | 0.84 | CLCN2 (0.45) | ALDH1A1HTTKDM4EHPGD | |
| SCHEMBL8654626 | 0.84 | GAA (0.56) | ALDH1A1GAASMN1; SMN2HTTRAB9A | |
| SCHEMBL10489704 | 0.82 | TRPV1 (0.45) | ALDH1A1GAARAB9ANPC1KMT2A | |
| SCHEMBL10489988 | 0.81 | FAAH (0.46) | ALDH1A1GAARAB9ANPC1KMT2A | |
| SCHEMBL10489667 | 0.80 | PPARA (0.49) | RAB9ANPC1PPARGNPSR1 | |
| SCHEMBL10489851 | 0.79 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2L3MBTL1RAB9ANPC1 | |
| SCHEMBL10489802 | 0.79 | PPARA (0.54) | PPARGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873232-A | ARTHRITIS AND AUTOIMMUNE DISEASES | SYNTEX (US) | 1989-10-10 | — | — | US | disclosed |