Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CLK1 | P49759 | 2/20 | 0.35 |
| ▸ | CLK2 | P49760 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10490481 | 0.81 | MEN1 (0.53) | TRPV3KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL14526063 | 0.79 | MAPT (0.51) | KDM4ELMNAMAPTALDH1A1CLK1 | |
| SCHEMBL10272516 | 0.79 | AURKA (0.53) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2759646 | 0.77 | NPC1 (0.58) | KDM4EMAPTALDH1A1CLK1CLK2 | |
| SCHEMBL3970473 | 0.72 | AURKA (0.53) | KDM4EMAPTMEN1KMT2ARAB9A | |
| SCHEMBL8842468 | 0.71 | MEN1 (0.50) | KDM4ELMNAMAPTALDH1A1MEN1 | |
| SCHEMBL10533031 | 0.70 | RAB9A (0.52) | KDM4ELMNAMAPTALDH1A1MEN1 | |
| SCHEMBL2759537 | 0.70 | HSP90AA1 (0.58) | KDM4ELMNAALDH1A1CLK1HSP90AA1 | |
| SCHEMBL22010374 | 0.70 | KMO (0.44) | TRPV3KDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL30892721 | 0.69 | ADORA2A (0.39) | KDM4EALDH1A1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4859670-A | 2-Azolylmethyl-2-aryl-1,3-dioxolanes and the salts thereof, agents containing same, and the use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-22 | — | — | US | disclosed |
| EP-0237962-A2 | 2-Azolylmethyl-2-aryl-1,3-dioxolanes and their preparation, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-23 | — | — | EP | disclosed |