Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SREBF2 | Q12772 | 2/20 | 0.47 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14526063 | 0.84 | MAPT (0.51) | MEN1KMT2ASREBF2KDM4ELMNA | |
| SCHEMBL10272516 | 0.83 | AURKA (0.53) | MEN1KMT2ASREBF2KDM4EALDH1A1 | |
| SCHEMBL10490263 | 0.81 | TRPV3 (0.37) | MEN1KMT2ASREBF2SREBF1KDM4E | |
| SCHEMBL2759646 | 0.81 | NPC1 (0.58) | MEN1KMT2ASREBF2KDM4EALDH1A1 | |
| SCHEMBL14148106 | 0.79 | MEN1 (0.50) | MEN1KMT2ASREBF2SREBF1KDM4E | |
| SCHEMBL28849660 | 0.78 | PIK3CA (0.50) | MEN1KMT2ASREBF2KDM4ELMNA | |
| SCHEMBL6508869 | 0.76 | MEN1 (0.82) | MEN1KMT2AKDM4ELMNAALDH1A1 | |
| SCHEMBL10194257 | 0.76 | KDM4E (0.62) | MEN1KMT2ASREBF2SREBF1KDM4E | |
| SCHEMBL2759537 | 0.74 | HSP90AA1 (0.58) | KDM4ELMNAALDH1A1ABL1BCR | |
| SCHEMBL22010374 | 0.74 | KMO (0.44) | MEN1KMT2AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4859670-A | 2-Azolylmethyl-2-aryl-1,3-dioxolanes and the salts thereof, agents containing same, and the use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-22 | — | — | US | disclosed |
| EP-0237962-A2 | 2-Azolylmethyl-2-aryl-1,3-dioxolanes and their preparation, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-23 | — | — | EP | disclosed |