SCHEMBL10490295

SCHEMBL10490295

CCOc1cc(C)nc2nc(S(=O)(=O)Cl)nn12

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
GLA P06280 1/20 0.42
LMNA P02545 1/20 0.41
KDM4E B2RXH2 2/20 0.39
MAPK1 P28482 2/20 0.38
MAPT P10636 1/20 0.38
ALDH1A1 P00352 2/20 0.38
USP2 O75604 1/20 0.38
HPGD P15428 2/20 0.37
GAA P10253 1/20 0.37
TSHR P16473 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
ALOX15 P16050 1/20 0.36
TP53 P04637 3/20 0.35
RECQL P46063 1/20 0.35
POLB P06746 1/20 0.34
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10490335 0.85 ALDH1A1 (0.45) MEN1KMT2AGLALMNAKDM4E
SCHEMBL1742675 0.78 LMNA (0.53) MEN1KMT2AGLALMNAKDM4E
SCHEMBL9679579 0.77 CKS1B (0.42) MEN1KMT2AGLALMNAKDM4E
SCHEMBL8354943 0.77 TSHR (0.42) MEN1KMT2AGLALMNAMAPK1
SCHEMBL8015385 0.77 L3MBTL1 (0.34) MEN1KMT2AGLAKDM4EMAPK1
SCHEMBL8355275 0.75 TSHR (0.41) MEN1KMT2AGLALMNAKDM4E
SCHEMBL8351311 0.74 TSHR (0.42) MEN1KMT2AGLALMNAKDM4E
SCHEMBL8351081 0.74 TSHR (0.42) MEN1KMT2AGLALMNAMAPK1
SCHEMBL9678995 0.73 MEN1 (0.42) MEN1KMT2AGLALMNAKDM4E
SCHEMBL8356670 0.73 TSHR (0.43) MEN1KMT2ALMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4886883-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1989-12-12 US claimed