Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 13/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.78 |
| ▸ | GAA | P10253 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.78 |
| ▸ | OGT | O15294 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30834681 | 0.88 | PSMB8 (1.00) | PSMB8KDM4EGAAALDH1A1OGT | |
| SCHEMBL97140 | 0.88 | PSMB8 (1.00) | PSMB8KDM4EGAAALDH1A1OGT | |
| SCHEMBL28808028 | 0.75 | PSMB8 (0.60) | PSMB8KDM4EGAAALDH1A1OGT | |
| SCHEMBL11323975 | 0.71 | KDM4E (0.61) | PSMB8KDM4EGAAALDH1A1OGT | |
| Benzoxazolinone SCHEMBL9110846 | 0.67 | OGT (1.00) | PSMB8KDM4EGAAALDH1A1OGT | |
| Benzoxazolinone SCHEMBL29475399 | 0.67 | OGT (1.00) | PSMB8KDM4EGAAALDH1A1OGT | |
| Benzoxazolinone SCHEMBL19555 | 0.67 | OGT (1.00) | PSMB8KDM4EGAAALDH1A1OGT | |
| Benzoxazolinone SCHEMBL3927631 | 0.67 | OGT (1.00) | PSMB8KDM4EGAAALDH1A1OGT | |
| SCHEMBL8697822 | 0.67 | PSMB8 (0.63) | PSMB8KDM4EGAAALDH1A1MEN1 | |
| SCHEMBL10897160 | 0.67 | PSMB8 (0.63) | PSMB8KDM4EGAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1022923-A | — | — | None | — | — | JP | disclosed |
| JP-S6422923-A | PRODUCTION OF POLYAMIDE | IDEMITSU KOSAN CO | 1989-01-25 | — | — | JP | disclosed |