Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | HRH1 | P35367 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8579882 | 0.81 | CYP3A4 (0.38) | CYP1A2CYP3A4TSHRCYP2C9CYP2C19 | |
| SCHEMBL10492513 | 0.80 | TYR (0.43) | CYP1A2CYP3A4TSHRALDH1A1ALOX15 | |
| SCHEMBL10492816 | 0.76 | CYP3A4 (0.40) | CYP1A2CYP3A4TSHRCYP2C9CYP2C19 | |
| SCHEMBL11706315 | 0.75 | HTR2A (0.45) | CYP1A2CYP3A4TSHRCYP2C9CYP2C19 | |
| SCHEMBL8130850 | 0.74 | CYP3A4 (0.43) | CYP3A4TSHRCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL2350960 | 0.72 | HTR2A (0.50) | CYP1A2CYP3A4TSHRCYP2C9CYP2C19 | |
| SCHEMBL10492874 | 0.72 | TDP1 (0.39) | CYP3A4ALDH1A1ALOX15TDP1MEN1 | |
| SCHEMBL5537841 | 0.71 | HKDC1 (0.46) | CYP1A2CYP3A4TSHRCYP2C9CYP2C19 | |
| SCHEMBL11205377 | 0.71 | HTR2A (0.54) | CYP1A2CYP3A4TSHRCYP2C9CYP2C19 | |
| SCHEMBL17836967 | 0.71 | HTR2A (0.45) | CYP1A2CYP3A4TSHRCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4868225-A | STERICALLY HINDERED META-PHENYLENEDIAMINE CHAIN EXTENDER FOR POLYURETHANES | THE DOW CHEMICAL COMPANY (US) | 1989-09-19 | — | — | US | disclosed |
| US-4866208-A | CURING AGENT FOR EPOXY RESINS; EXTENDERS FOR POLYUREA-URETHANE COPOLYMERS | THE DOW CHEMICAL COMPANY (US) | 1989-09-12 | — | — | US | disclosed |
| US-4792623-A | CURING AGENT, EXTENDER | THE DOW CHEMICAL COMPANY (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0082258-B1 | SUBSTITUTED M-PHENYLENEDIAMINES | THE DOW CHEMICAL COMPANY (US) | 1986-02-19 | — | — | EP | disclosed |
| EP-0082258-A1 | Substituted m-phenylenediamines | THE DOW CHEMICAL COMPANY (US) | 1983-06-29 | — | — | EP | disclosed |