Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.45 |
| ▸ | HRH1 | P35367 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28261050 | 0.87 | TSHR (0.48) | HTR2AHRH1LMNATAAR1TDP1 | |
| SCHEMBL11205377 | 0.84 | HTR2A (0.54) | HTR2AHRH1LMNATAAR1TDP1 | |
| SCHEMBL11706315 | 0.83 | HTR2A (0.45) | HTR2AHRH1LMNATAAR1TDP1 | |
| SCHEMBL7645209 | 0.82 | ALDH1A1 (0.37) | HTR2AHRH1LMNATAAR1TDP1 | |
| SCHEMBL20696107 | 0.80 | TSHR (0.53) | HTR2AHRH1LMNATAAR1TDP1 | |
| SCHEMBL10777918 | 0.80 | CYP1A2 (0.42) | LMNATDP1TSHRCYP1A2 | |
| SCHEMBL486873 | 0.78 | TSHR (0.42) | HTR2AHRH1LMNATAAR1TDP1 | |
| SCHEMBL6542924 | 0.78 | CD44 (0.43) | LMNATAAR1TDP1TSHRCYP1A2 | |
| SCHEMBL54346 | 0.78 | HTR2A (0.59) | HTR2AHRH1LMNATAAR1TDP1 | |
| SCHEMBL17064323 | 0.77 | HTR2A (0.43) | HTR2AHRH1LMNATAAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9656256-B2 | N-heterocyclic carbene type palladium catalyst and its preparation method as well as applications | SHANGHAI RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2017-05-23 | — | — | US | disclosed |
| US-20160175828-A1 | N-HETEROCYCLIC CARBENE TYPE PALLADIUM CATALYST AND ITS PREPARATION METHOD AS WELL AS APPLICATIONS | SHANGHAI RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2016-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160175828-A1 | N-HETEROCYCLIC CARBENE TYPE PALLADIUM CATALYST AND ITS PREPARATION METHOD AS WELL AS APPLICATIONS | DDC, AOC1, GNE | HTR2A 2326/4885HRH1 200/4885LMNA 2024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.