Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.51 |
| ▸ | F2 | P00734 | 8/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 7/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 7/20 | 0.51 |
| ▸ | ST14 | Q9Y5Y6 | 5/20 | 0.51 |
| ▸ | PLG | P00747 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HGFAC | Q04756 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.50 |
| ▸ | MLNR | O43193 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | C1R | P00736 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | F12 | P00748 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perchlorate SCHEMBL11147214 | 0.92 | PARP10 (0.46) | PARP10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL29009176 | 0.87 | KMT2A (0.61) | PARP10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL2838573 | 0.87 | KMT2A (0.61) | PARP10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL9342118 | 0.84 | PRSS1 (0.64) | PARP10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7744358 | 0.84 | PARP10 (0.74) | PARP10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL10891811 | 0.83 | PRSS1 (0.65) | PARP10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL10890871 | 0.83 | PRSS1 (0.72) | PARP10PRSS1F2PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL10941768 | 0.83 | PRSS1 (0.62) | PARP10PRSS1F2PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL3402436 | 0.83 | PARP10 (0.72) | PARP10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL5330655 | 0.82 | PARP10 (0.66) | PARP10PRSS1F2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4808405-A | ANTICOAGULANT | BEECHAM GROUP P.L.C. (GB) | 1989-02-28 | — | — | US | disclosed |
| EP-0151593-B1 | ENZYME DERIVATIVES | BEECHAM GROUP PLC (GB) | 1989-02-22 | — | — | EP | disclosed |
| US-4604285-A | ANTICOAGULANT | BEECHAM GROUP P.L.C. (GB) | 1986-08-05 | — | — | US | disclosed |
| EP-0151593-A1 | ENZYME DERIVATIVES. | BEECHAM GROUP PLC (GB) | 1985-08-21 | — | — | EP | disclosed |
| WO-1985000521-A1 | ENZYME DERIVATIVES | BEECHAM GROUP P.L.C. (GB) | 1985-02-14 | — | — | WO | disclosed |
| EP-0009879-B1 | ENZYME DERIVATIVES FOR USE IN THE TREATMENT OF VENOUS THROMBOSIS, COMPOSITIONS CONTAINING THEM AND THEIR PREPARATION | BEECHAM GROUP PLC (GB) | 1983-10-12 | — | — | EP | disclosed |
| EP-0028489-B1 | ENZYME DERIVATIVES, AND THEIR PREPARATION | BEECHAM GROUP PLC (GB) | 1983-10-05 | — | — | EP | disclosed |
| US-4337244-A | COMPRISING A FIBRINOLYTIC ENZYME BLOCKED BY AN END GROUP REMOVABLE BY HYDROLYSIS | BEECHAM GROUP LIMITED (GB) | 1982-06-29 | — | — | US | disclosed |
| US-4285932-A | Enzyme derivatives for use in the treatment of venous thrombosis | BEECHAM GROUP LIMITED (GB) | 1981-08-25 | — | — | US | disclosed |
| EP-0028489-A1 | Enzyme derivatives, and their preparation | BEECHAM GROUP PLC (GB) | 1981-05-13 | — | — | EP | disclosed |
| EP-0009879-A1 | Enzyme derivatives for use in the treatment of venous thrombosis, compositions containing them and their preparation | BEECHAM GROUP PLC (GB) | 1980-04-16 | — | — | EP | disclosed |