Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.66 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.63 |
| ▸ | TMPRSS15 | P98073 | 5/20 | 0.63 |
| ▸ | ACR | P10323 | 1/20 | 0.63 |
| ▸ | F2 | P00734 | 2/20 | 0.54 |
| ▸ | F10 | P00742 | 1/20 | 0.54 |
| ▸ | F12 | P00748 | 1/20 | 0.54 |
| ▸ | F7 | P08709 | 1/20 | 0.54 |
| ▸ | F3 | P13726 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | WDR5 | P61964 | 1/20 | 0.52 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | C1S | P09871 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744358 | 0.95 | PARP10 (0.74) | PARP10PRSS1TMPRSS15ACRF2 | |
| Hydrochloric Acid SCHEMBL3402436 | 0.93 | PARP10 (0.72) | PARP10PRSS1TMPRSS15ACRF2 | |
| SCHEMBL20008705 | 0.86 | PLAU (0.61) | PARP10PRSS1TMPRSS15ACRF2 | |
| SCHEMBL70034 | 0.86 | PARP10 (0.70) | PARP10PRSS1TMPRSS15ACRF2 | |
| SCHEMBL11272755 | 0.85 | PARP10 (0.89) | PARP10PRSS1TMPRSS15ACRF2 | |
| SCHEMBL9342118 | 0.84 | PRSS1 (0.64) | PARP10PRSS1TMPRSS15F2F10 | |
| Carbamic Acid Phenyl Ester SCHEMBL10553901 | 0.83 | F10 (0.61) | PARP10PRSS1TMPRSS15F2F10 | |
| SCHEMBL10492899 | 0.82 | PARP10 (0.53) | PARP10PRSS1TMPRSS15F2F10 | |
| SCHEMBL10890871 | 0.82 | PRSS1 (0.72) | PARP10PRSS1ACRF2MAPT | |
| SCHEMBL10891811 | 0.82 | PRSS1 (0.65) | PARP10PRSS1TMPRSS15ACRF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039151-A1 | BLOCKERS OF TRANSFORMING GROWTH FACTOR BETA AND ITS RECEPTORS FOR THE TREATMENT OF INFECTIOUS DISEASES | Universität Zürich (CH) | 2007-04-12 | — | — | WO | claimed |
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2018-03-29 | — | — | US | disclosed |
| US-20150275306-A1 | METHODS AND MEANS FOR PREDICTING RESISTANCE TO ANTI-CANCER TREATMENT | AGENDIA N.V. (NL) | 2015-10-01 | — | — | US | disclosed |
| WO-2007039151-A1 | BLOCKERS OF TRANSFORMING GROWTH FACTOR BETA AND ITS RECEPTORS FOR THE TREATMENT OF INFECTIOUS DISEASES | Universität Zürich (CH) | 2007-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | OPRM1, OPRK1, OPRD1 | PARP10 3466/4885PRSS1 952/4885TMPRSS15 87/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.