Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 4/20 | 0.72 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.72 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.72 |
| ▸ | ACR | P10323 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | PTGIR | P43119 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.56 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.56 |
| ▸ | NQO2 | P16083 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12608584 | 0.87 | LMNA (0.75) | PRSS1ACRLMNACYP1A2CYP2C9 | |
| SCHEMBL12633724 | 0.87 | LMNA (0.75) | PRSS1ACRLMNACYP1A2CYP2C9 | |
| SCHEMBL7591660 | 0.87 | LMNA (0.75) | PRSS1ACRLMNACYP1A2CYP2C9 | |
| SCHEMBL9666088 | 0.87 | LMNA (0.75) | PRSS1ACRLMNACYP1A2CYP2C9 | |
| SCHEMBL10891811 | 0.86 | PRSS1 (0.65) | PRSS1PRSS2PRSS3ACRLMNA | |
| SCHEMBL428892 | 0.85 | PRSS1 (1.00) | PRSS1PRSS2PRSS3PTGIRPARP10 | |
| SCHEMBL9342118 | 0.84 | PRSS1 (0.64) | PRSS1PRSS2PRSS3LMNAKMT2A | |
| SCHEMBL7744358 | 0.84 | PARP10 (0.74) | PRSS1PRSS2PRSS3ACRKMT2A | |
| Hydrochloric Acid SCHEMBL2570665 | 0.83 | PRSS1 (0.95) | PRSS1PRSS2PRSS3PTGIRPARP10 | |
| Hydrochloric Acid SCHEMBL3402436 | 0.83 | PARP10 (0.72) | PRSS1PRSS2PRSS3ACRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4604285-A | ANTICOAGULANT | BEECHAM GROUP P.L.C. (GB) | 1986-08-05 | — | — | US | disclosed |