Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.74 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.57 |
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.57 |
| ▸ | F2 | P00734 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | F10 | P00742 | 1/20 | 0.57 |
| ▸ | F12 | P00748 | 1/20 | 0.57 |
| ▸ | F7 | P08709 | 1/20 | 0.57 |
| ▸ | F3 | P13726 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | ACR | P10323 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.53 |
| ▸ | C1S | P09871 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3402436 | 0.98 | PARP10 (0.72) | PARP10PRSS1TMPRSS15F2PKM | |
| SCHEMBL5330655 | 0.95 | PARP10 (0.66) | PARP10PRSS1TMPRSS15F2PKM | |
| SCHEMBL9663679 | 0.87 | PARP10 (0.81) | PARP10PRSS1TMPRSS15F2PKM | |
| SCHEMBL9342118 | 0.86 | PRSS1 (0.64) | PARP10PRSS1TMPRSS15F2PKM | |
| SCHEMBL7337750 | 0.85 | F12 (0.71) | PARP10PRSS1F2F10F12 | |
| SCHEMBL23486305 | 0.85 | PARP10 (1.00) | PARP10PRSS1TMPRSS15F2PKM | |
| SCHEMBL8205435 | 0.85 | PARP10 (0.78) | PARP10PRSS1TMPRSS15F2PKM | |
| SCHEMBL725405 | 0.84 | PARP10 (0.77) | PARP10PRSS1TMPRSS15F2PKM | |
| SCHEMBL10492899 | 0.84 | PARP10 (0.53) | PARP10PRSS1TMPRSS15F2F10 | |
| SCHEMBL10890871 | 0.84 | PRSS1 (0.72) | PARP10PRSS1F2KMT2AACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230241054-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2023-08-03 | — | — | US | disclosed |
| US-20210403420-A1 | BENZOATE COMPOUND | SCOHIA PHARMA, INC. (JP) | 2021-12-30 | — | — | US | disclosed |
| US-11129825-B2 | Polysubunit opioid prodrugs resistant to overdose and abuse | ELYSIUM THERAPEUTICS, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| US-20190183884-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2019-06-20 | — | — | US | disclosed |
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2018-03-29 | — | — | US | disclosed |
| US-20170100390-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2017-04-13 | — | — | US | disclosed |
| EP-2669683-A1 | METHOD AND APPARATUS FOR MEASURING PHYSIOLOGICALLY ACTIVE BIOLOGICAL SUBSTANCE | Kowa Company Ltd. (JP) | 2013-12-04 | — | — | EP | disclosed |
| US-20130309704-A1 | METHOD AND APPARATUS FOR MEASURING PHYSIOLOGICALLY ACTIVE SUBSTANCE DERIVED FROM ORGANISM | KOWA COMPANY, LTD. (JP) | 2013-11-21 | — | — | US | disclosed |
| US-7671057-B2 | Therapeutic agent for type II diabetes comprising protease-inhibiting compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-03-02 | — | — | US | disclosed |
| US-20080009537-A1 | Therapeutic Agent for Diabetes Comprising Protease-Inhibiting Compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-01-10 | — | — | US | disclosed |
| EP-0151593-B1 | ENZYME DERIVATIVES | BEECHAM GROUP PLC (GB) | 1989-02-22 | — | — | EP | disclosed |
| US-4604285-A | ANTICOAGULANT | BEECHAM GROUP P.L.C. (GB) | 1986-08-05 | — | — | US | disclosed |
| EP-0151593-A1 | ENZYME DERIVATIVES. | BEECHAM GROUP PLC (GB) | 1985-08-21 | — | — | EP | disclosed |
| WO-1985000521-A1 | ENZYME DERIVATIVES | BEECHAM GROUP P.L.C. (GB) | 1985-02-14 | — | — | WO | disclosed |
| EP-0009879-B1 | ENZYME DERIVATIVES FOR USE IN THE TREATMENT OF VENOUS THROMBOSIS, COMPOSITIONS CONTAINING THEM AND THEIR PREPARATION | BEECHAM GROUP PLC (GB) | 1983-10-12 | — | — | EP | disclosed |
| EP-0028489-B1 | ENZYME DERIVATIVES, AND THEIR PREPARATION | BEECHAM GROUP PLC (GB) | 1983-10-05 | — | — | EP | disclosed |
| US-4337244-A | COMPRISING A FIBRINOLYTIC ENZYME BLOCKED BY AN END GROUP REMOVABLE BY HYDROLYSIS | BEECHAM GROUP LIMITED (GB) | 1982-06-29 | — | — | US | disclosed |
| US-4285932-A | Enzyme derivatives for use in the treatment of venous thrombosis | BEECHAM GROUP LIMITED (GB) | 1981-08-25 | — | — | US | disclosed |
| EP-0028489-A1 | Enzyme derivatives, and their preparation | BEECHAM GROUP PLC (GB) | 1981-05-13 | — | — | EP | disclosed |
| EP-0009879-A1 | Enzyme derivatives for use in the treatment of venous thrombosis, compositions containing them and their preparation | BEECHAM GROUP PLC (GB) | 1980-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | OPRM1, OPRK1, OPRD1 | PARP10 3466/4885PRSS1 952/4885TMPRSS15 87/4885 |
| US-20210403420-A1 | BENZOATE COMPOUND | TMPRSS15, DPP4, DPP3 | PARP10 4012/4885PRSS1 103/4885TMPRSS15 1/4885 |
| US-20080009537-A1 | Therapeutic Agent for Diabetes Comprising Protease-Inhibiting Compound | DPP4, IAPP, DPP7 | PARP10 4122/4885PRSS1 25/4885TMPRSS15 21/4885 |
| US-20170100390-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | OPRK1, OPRM1, CYP3A5 | PARP10 1884/4885PRSS1 717/4885TMPRSS15 173/4885 |
| US-20230241054-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | OPRK1, OPRM1, CYP3A5 | PARP10 1884/4885PRSS1 717/4885TMPRSS15 173/4885 |
| US-11129825-B2 | Polysubunit opioid prodrugs resistant to overdose and abuse | OPRK1, OPRM1, CYP3A5 | PARP10 1884/4885PRSS1 717/4885TMPRSS15 173/4885 |
| US-20190183884-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | OPRK1, OPRM1, CYP3A5 | PARP10 1884/4885PRSS1 717/4885TMPRSS15 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.