Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.37 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10493322 | 0.93 | CTSL (0.40) | ATMCTSLCTSSMAPTPDE3A | |
| SCHEMBL11266202 | 0.87 | CTSL (0.38) | CTSLCTSSMAPTPDE3ASLC22A6 | |
| SCHEMBL11423312 | 0.84 | MAPT (0.39) | ATMMAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL11423317 | 0.84 | MAPT (0.39) | ATMMAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL8597022 | 0.83 | ATM (0.42) | ATMMAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL7828421 | 0.83 | ATM (0.42) | ATMMAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL10873072 | 0.82 | ALOX5 (0.44) | SMN1; SMN2 | |
| Water SCHEMBL8600954 | 0.82 | ATM (0.42) | ATMCTSSMAPTPDE3ASLC22A6 | |
| SCHEMBL10873068 | 0.81 | MMP2 (0.42) | — | |
| SCHEMBL9567734 | 0.81 | MAPT (0.46) | ATMMAPTPDE3ASLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4877783-A | β-lactam antibacterial agents | BEECHAM GROUP P.L.C. (GB) | 1989-10-31 | — | — | US | disclosed |
| US-4684641-A | BACTERICIDES | PFIZER INC. (US) | 1987-08-04 | — | — | US | disclosed |
| US-4609652-A | FORMAMIDYL DERIVATIVES OF AMINO ACID DERIVATIVE ANTIBIOTICS | BEECHAM GROUP P.L.C. (GB) | 1986-09-02 | — | — | US | disclosed |
| EP-0168177-A2 | Cephalosporin antibiotics | Pfizer Limited (GB) | 1986-01-15 | — | — | EP | disclosed |
| US-4539149-A | β-Lactam antibacterial agents | BEECHAM GROUP P.L.C. (GB) | 1985-09-03 | — | — | US | disclosed |
| EP-0071395-A1 | Beta-lactam antibacterial agents | BEECHAM GROUP PLC (GB) | 1983-02-09 | — | — | EP | disclosed |