Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | PLK1 | P53350 | 2/20 | 0.46 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | FOS | P01100 | 1/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10497432 | 0.90 | CYSLTR2 (0.52) | BCHEALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL10499064 | 0.88 | CYSLTR2 (0.52) | BCHEALDH1A1KDM4ECYSLTR2 | |
| SCHEMBL10497836 | 0.87 | P4HB (0.47) | ALDH1A1LMNACYP1A2EGFRKDM4E | |
| SCHEMBL10497777 | 0.87 | THRA (0.46) | CYP1A2THRATHRB | |
| SCHEMBL10498322 | 0.86 | HDAC4 (0.47) | CYP1A2THRATHRB | |
| SCHEMBL9339939 | 0.86 | MAOB (0.54) | MAOBBCHEALDH1A1GAAHTT | |
| SCHEMBL9342494 | 0.85 | CYSLTR2 (0.52) | BCHEALDH1A1KDM4ETHRATHRB | |
| SCHEMBL9338557 | 0.85 | CYSLTR2 (0.52) | BCHEALDH1A1KDM4ETHRATHRB | |
| SCHEMBL9337916 | 0.85 | CYSLTR2 (0.52) | BCHEALDH1A1KDM4ETHRATHRB | |
| SCHEMBL9337348 | 0.85 | CYSLTR2 (0.52) | BCHEALDH1A1KDM4ETHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |