Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | TACR2 | P21452 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TST | Q16762 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10497777 | 0.90 | THRA (0.46) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10498322 | 0.89 | HDAC4 (0.47) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10498288 | 0.88 | SLC6A19 (0.45) | LMNATHRATHRBATG4BPLA2G1B | |
| SCHEMBL10498154 | 0.88 | THRA (0.44) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497360 | 0.87 | MAOB (0.48) | KDM4EALDH1A1LMNAEGFRTHRA | |
| SCHEMBL10497663 | 0.87 | THRA (0.43) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497705 | 0.87 | THRA (0.44) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497432 | 0.86 | CYSLTR2 (0.52) | KDM4EALDH1A1LMNACYP3A4ACHE | |
| SCHEMBL9342510 | 0.85 | HDAC4 (0.43) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497586 | 0.85 | MAOA (0.43) | EGFRTHRATHRBATG4BPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |