Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10499142 | 0.86 | ALDH1A1 (0.51) | ALDH1A1TDP1NPC1RECQLRAB9A | |
| SCHEMBL10498256 | 0.80 | GPR35 (0.45) | GPR35TSHRALDH1A1TDP1NPC1 | |
| SCHEMBL1459508 | 0.78 | GPR35 (0.49) | GPR35TSHRALDH1A1TDP1NPC1 | |
| SCHEMBL10497989 | 0.76 | ALDH1A1 (0.41) | TSHRALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL17626963 | 0.75 | TSHR (0.50) | GPR35TSHRALDH1A1TDP1NPC1 | |
| SCHEMBL6136622 | 0.75 | GPR35 (0.57) | GPR35TSHRALDH1A1TDP1NPC1 | |
| SCHEMBL1161927 | 0.73 | TDP1 (0.71) | GPR35TSHRALDH1A1TDP1NPC1 | |
| SCHEMBL29603881 | 0.73 | TDP1 (0.71) | GPR35TSHRALDH1A1TDP1NPC1 | |
| SCHEMBL10498195 | 0.73 | HSPB1 (0.51) | GPR35TSHRALDH1A1TDP1HSPB1 | |
| SCHEMBL11278513 | 0.73 | TSHR (0.47) | GPR35TSHRALDH1A1TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4886516-A | Diaminotetrafluoroethoxybenzenes, process for producing same and hair coloring agents containing same | WELLA AKTIENGESELLSCHAFT (DE) | 1989-12-12 | — | — | US | disclosed |
| US-4845294-A | COUPLERS IN OXIDATIVE HAIR COLORING AGENTS | WELLA AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |