Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10498263 | 0.86 | GPR35 (0.44) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL1424469 | 0.82 | ALDH1A1 (0.58) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL10498195 | 0.80 | HSPB1 (0.51) | ALDH1A1TDP1HPGDPOLBHTT | |
| SCHEMBL29135344 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL10498015 | 0.78 | TSHR (0.53) | ALDH1A1TDP1NPC1RAB9AHPGD | |
| SCHEMBL10498143 | 0.78 | TSHR (0.53) | ALDH1A1NPC1L3MBTL1KMT2AMEN1 | |
| SCHEMBL10499130 | 0.78 | ALDH1A1 (0.53) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL2164883 | 0.78 | ULK1 (0.33) | ALDH1A1KMT2A | |
| SCHEMBL10498248 | 0.75 | CYP1A2 (0.38) | ALDH1A1TDP1RECQLHPGDHTT | |
| SCHEMBL27990079 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TDP1NPC1RAB9ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4886516-A | Diaminotetrafluoroethoxybenzenes, process for producing same and hair coloring agents containing same | WELLA AKTIENGESELLSCHAFT (DE) | 1989-12-12 | — | — | US | disclosed |
| US-4845294-A | COUPLERS IN OXIDATIVE HAIR COLORING AGENTS | WELLA AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |