Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A19 | Q695T7 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 11/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 9/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10497777 | 0.90 | THRA (0.46) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10498322 | 0.89 | HDAC4 (0.47) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497836 | 0.88 | P4HB (0.47) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10498154 | 0.88 | THRA (0.44) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497705 | 0.87 | THRA (0.44) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497663 | 0.87 | THRA (0.43) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497528 | 0.86 | THRA (0.47) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL9338032 | 0.86 | THRA (0.47) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497516 | 0.85 | THRA (0.44) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL9342510 | 0.85 | HDAC4 (0.43) | THRATHRBATG4BPLA2G1BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |