Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 10/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GUSB | P08236 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL637824 | 0.88 | KDM4E (0.47) | CTSDL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL172248 | 0.76 | CYP19A1 (0.61) | CTSDL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL171844 | 0.76 | CTSD (0.52) | CTSDL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL30172357 | 0.74 | ESR2 (0.53) | CTSDL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL13376084 | 0.73 | HTT (0.56) | CTSDL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL30530929 | 0.73 | CTSD (0.50) | CTSDL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL29470569 | 0.73 | CTSD (0.50) | CTSDL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL7458014 | 0.72 | ALDH1A1 (0.60) | KDM4EALDH1A1HPGDHTTHSD17B10 | |
| SCHEMBL4496900 | 0.72 | KDM4E (0.49) | CTSDL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL13351524 | 0.72 | ALDH1A1 (0.66) | CTSDL3MBTL1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0138034-B1 | Substituted pyrido[1,2-c]imidazo[1,2-a]benzimidazoles, process for their preparation, their use and pharmaceutical preparations containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-29 | — | — | EP | claimed |