SCHEMBL7458014

SCHEMBL7458014

Nc1ccc(-c2nc3ccccc3n2[S+]([O-])n2c(-c3ccc(N)cc3)nc3ccccc32)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 11/20 0.60
▸ KDM4E B2RXH2 8/20 0.60
▸ RAB9A P51151 8/20 0.60
▸ NPC1 O15118 5/20 0.60
▸ PKM P14618 4/20 0.60
▸ TP53 P04637 4/20 0.60
▸ HSD17B10 Q99714 4/20 0.60
▸ GAA P10253 2/20 0.60
▸ ALOX15 P16050 1/20 0.60
▸ HPGD P15428 7/20 0.56
▸ SMN1; SMN2 Q16637 5/20 0.52
▸ MAPT P10636 4/20 0.52
▸ RAD51 Q06609 1/20 0.47
▸ CA1 P00915 1/20 0.43
▸ CA2 P00918 1/20 0.43
▸ KMT2A Q03164 5/20 0.42
▸ MEN1 O00255 4/20 0.42
▸ LMNA P02545 3/20 0.42
▸ RXFP1 Q9HBX9 1/20 0.40
▸ HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6439288 0.77 ALDH1A1 (0.68) ALDH1A1KDM4ERAB9ANPC1PKM
SCHEMBL9520082 0.76 KDM4E (0.71) ALDH1A1KDM4ERAB9ANPC1PKM
SCHEMBL31474745 0.76 ALDH1A1 (1.00) ALDH1A1KDM4ERAB9ANPC1PKM
SCHEMBL9705114 0.76 ALDH1A1 (1.00) ALDH1A1KDM4ERAB9ANPC1PKM
SCHEMBL27578529 0.74 KDM4E (0.49) ALDH1A1KDM4ERAB9ANPC1PKM
SCHEMBL2605804 0.73 ESR1 (0.63) ALDH1A1KDM4ERAB9ANPC1PKM
SCHEMBL10499384 0.72 CTSD (0.49) ALDH1A1KDM4ENPC1TP53HSD17B10
SCHEMBL11955410 0.72 ESR1 (0.61) ALDH1A1KDM4ERAB9ANPC1PKM
SCHEMBL21777019 0.72 KDM4E (1.00) ALDH1A1KDM4ERAB9ANPC1PKM
SCHEMBL17226245 0.70 ESR2 (0.72) ALDH1A1KDM4ERAB9ANPC1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6482569-B1 Process for forming a polyimide pattern with photosensitive composition for i-line stepper ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-11-19 — — US disclosed
EP-0718696-B1 Photosensitive polyimide precursor composition ASAHI CHEMICAL IND (JP) 2002-01-16 — — EP disclosed
US-6162580-A Photosensitive polyimide precursor compositions processable by exposure to short wavelength light ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2000-12-19 — — US disclosed
EP-0580108-B1 A photosensitive polyimide composition ASAHI CHEMICAL IND (JP) 1997-03-12 — — EP disclosed
EP-0718696-A2 A photosensitive polyimide composition ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1996-06-26 — — EP disclosed
EP-0580108-A2 A photosensitive polyimide composition ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1994-01-26 — — EP disclosed
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