SCHEMBL10499692

SCHEMBL10499692

O=[N+]([O-])c1occc1CCl

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
ALDH1A1 P00352 1/20 0.46
PAX8 Q06710 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12818676 0.80 HSP90AA1 (0.36) TSHRALDH1A1PAX8
SCHEMBL826470 0.72
SCHEMBL9684858 0.70 TDP1 (0.39) TSHRALDH1A1PAX8
SCHEMBL6168612 0.68
SCHEMBL11127754 0.68
SCHEMBL7022043 0.64 LMNA (0.47) ALDH1A1
SCHEMBL11879583 0.63 CA2 (0.42) ALDH1A1
SCHEMBL8461057 0.63 TSHR (0.59) TSHRALDH1A1
SCHEMBL9686374 0.63
SCHEMBL69613 0.63 ALDH1A1 (1.00) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4835312-A Production process of N-substituted amide compounds MITSUI CHEMICALS, INCORPORATED (JP) 1989-05-30 US disclosed