Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.54 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | F3 | P13726 | 2/20 | 0.54 |
| ▸ | TNKS | O95271 | 1/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29210192 | 1.00 | MAPT (0.54) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL869685 | 0.80 | MAPT (0.58) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL1999708 | 0.80 | MAPT (0.58) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL12261578 | 0.80 | MAPT (0.58) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL1999706 | 0.80 | MAPT (0.58) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL28877689 | 0.79 | TYR (0.56) | MAPTHDAC6LMNAALDH1A1F3 | |
| SCHEMBL7936575 | 0.79 | MAPT (0.57) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL375054 | 0.79 | MAPT (0.57) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL4856786 | 0.78 | MAPT (0.56) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL22771499 | 0.78 | MAPT (0.56) | MAPTHDAC3HDAC4HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396141-A | Preparation method of bromine chloride or bromine azide | 中国科学技术大学 | 2023-07-07 | — | — | CN | disclosed |
| CN-111233618-B | Method for preparing chloroethylene compounds by using phosgene | 浙江新和成股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-111233618-A | Method for preparing chloroethylene compounds by using phosgene | 浙江新和成股份有限公司 | 2020-06-05 | — | — | CN | disclosed |
| US-4835312-A | Production process of N-substituted amide compounds | MITSUI CHEMICALS, INCORPORATED (JP) | 1989-05-30 | — | — | US | disclosed |