SCHEMBL28877689

SCHEMBL28877689

C=C(Cl)C=Cc1ccc(O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 4/20 0.56
CYP2C9 P11712 3/20 0.56
F3 P13726 2/20 0.56
CYP2D6 P10635 2/20 0.56
HSD11B1 P28845 1/20 0.56
CA12 O43570 4/20 0.54
CA1 P00915 4/20 0.54
CA2 P00918 4/20 0.54
CA7 P43166 4/20 0.54
CA9 Q16790 4/20 0.54
CA14 Q9ULX7 4/20 0.54
AKR1B1 P15121 3/20 0.54
CA3 P07451 3/20 0.54
CA4 P22748 3/20 0.54
CA6 P23280 3/20 0.54
CA5A P35218 3/20 0.54
CA5B Q9Y2D0 3/20 0.54
PKM P14618 3/20 0.54
AKR1B10 O60218 2/20 0.54
ESR1 P03372 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16067308 0.79 TYR (0.61) TYRCYP2C9F3CYP2D6HSD11B1
SCHEMBL29210192 0.79 MAPT (0.54) CYP2C9F3CYP2D6CA1HCAR2
SCHEMBL10499802 0.79 MAPT (0.54) CYP2C9F3CYP2D6CA1HCAR2
SCHEMBL2033989 0.77 TYR (0.68) TYRCYP2C9F3CYP2D6HSD11B1
SCHEMBL7871863 0.77 TYR (0.68) TYRCYP2C9F3CYP2D6HSD11B1
SCHEMBL12261582 0.77 LMNA (0.59) TYRCYP2C9F3CYP2D6HSD11B1
SCHEMBL11773809 0.77 LMNA (0.59) TYRCYP2C9F3CYP2D6HSD11B1
SCHEMBL12453517 0.76 F3 (0.59) TYRCYP2C9F3CYP2D6HSD11B1
SCHEMBL14548003 0.76 AKR1B10 (0.61) TYRCYP2C9F3CYP2D6HSD11B1
Trans-4,4'-Dihydroxystilbene SCHEMBL13339135 0.74 APP (0.74) TYRCYP2C9F3CYP2D6HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110352212-A Acrylic resin biaxially-stretched film and its manufacturing method 株式会社可乐丽 2019-10-18 CN disclosed