Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713703 | 0.84 | ABCB11 (0.51) | PDE7APDE7BL3MBTL1MAPK1KMT2A | |
| SCHEMBL10503448 | 0.83 | MAPT (0.43) | KMT2AMAPTMEN1ALOX15HSD17B10 | |
| SCHEMBL30226615 | 0.81 | PDE7A (0.39) | PDE7APDE7BL3MBTL1MAPK1KMT2A | |
| SCHEMBL9713758 | 0.81 | L3MBTL1 (0.48) | PDE7APDE7BL3MBTL1MAPK1KMT2A | |
| SCHEMBL9713839 | 0.78 | L3MBTL1 (0.46) | L3MBTL1MAPK1KMT2AMAPTMEN1 | |
| SCHEMBL29372079 | 0.78 | ABCB11 (0.49) | KMT2AMAPTMEN1ALOX15HSD17B10 | |
| SCHEMBL30226594 | 0.77 | ABCB11 (0.43) | PDE7APDE7BL3MBTL1MAPK1KMT2A | |
| SCHEMBL9643565 | 0.73 | ABCB11 (0.67) | L3MBTL1KMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL9643247 | 0.72 | ABCB11 (0.47) | L3MBTL1MAPK1KMT2AMAPTMEN1 | |
| SCHEMBL9643206 | 0.72 | ABCB11 (0.44) | KMT2AMAPTMEN1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |