SCHEMBL1050397

SCHEMBL1050397

CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)[C@@H]3CC[C@H]4C(C)(C)CCC[C@@]45C[C@]35CC[C@]12C

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ ACLY P53396 2/20 0.48
▸ ACACA Q13085 2/20 0.48
▸ EBP Q15125 8/20 0.48
▸ CDC25A P30304 8/20 0.44
▸ CDC25B P30305 8/20 0.44
▸ PTPN11 Q06124 1/20 0.40
▸ HSD11B1 P28845 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL300737 1.00 ACLY (0.48) ACLYACACAEBPCDC25ACDC25B
SCHEMBL29934951 0.87 CDC25A (0.59) ACLYACACAEBPCDC25ACDC25B
SCHEMBL14116745 0.85 CDC25A (0.51) ACLYACACAEBPCDC25ACDC25B
SCHEMBL3285801 0.84 ACLY (0.61) ACLYACACAEBPPTPN11HSD11B1
SCHEMBL3285804 0.84 ACLY (0.61) ACLYACACAEBPPTPN11HSD11B1
SCHEMBL2450676 0.82 CDC25A (0.46) ACLYACACAEBPCDC25ACDC25B
SCHEMBL2450675 0.82 CDC25A (0.46) ACLYACACAEBPCDC25ACDC25B
Cycloartanol SCHEMBL12152356 0.81 ACLY (0.67) ACLYACACAEBPCDC25ACDC25B
Cycloartanol SCHEMBL1881616 0.81 ACLY (0.67) ACLYACACAEBPCDC25ACDC25B
Cycloartanol SCHEMBL13801860 0.81 ACLY (0.67) ACLYACACAEBPCDC25ACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59036623-A — — None — — JP disclosed
US-20110020226-A1 PARTICLE STRUCTURES COMPRISING STEROLS AND SAPONINS NORDIC VACCINE TECHNOLOGY A/S 2011-01-27 — — US disclosed
US-7713942-B2 Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides NORDIC VACCINE TECHNOLOGY A/S (DK) 2010-05-11 — — US disclosed
EP-2011517-A1 Polynucleotide binding complexes comprising sterols and saponin Nordic Vaccine Technology A/S (DK) 2009-01-07 — — EP disclosed
EP-1377320-B1 POLYNUCLEOTIDE BINDING COMPLEXES COMPRISING STEROLS AND SAPONINS NORDIC VACCINE TECHNOLOGY AS (DK) 2008-10-01 — — EP disclosed
US-20040185057-A1 Therapeutical vaccination NORDIC VACCINE TECHNOLOGY A/S (DK) 2004-09-23 — — US disclosed
EP-1409009-A1 THERAPEUTICAL VACCINATION Nordic Vaccine Technology A/S (DK) 2004-04-21 — — EP disclosed
US-20030118635-A1 Polynucleotide binding complexes comprising sterols and saponins ISCONOVA AB (SE) 2003-06-26 — — US disclosed
WO-2002102407-A1 THERAPEUTICAL VACCINATION NORDIC VACCINE TECHNOLOGY A/S (DK) 2002-12-27 — — WO disclosed
JP-S5936623-A INDUCING AGENT FOR INTERFERON ZENYAKU KOGYO KK 1984-02-28 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110020226-A1 PARTICLE STRUCTURES COMPRISING STEROLS AND SAPONINS LSS, SNRPE, HLA-C ACLY 694/4885ACACA 1098/4885EBP 500/4885
US-20030118635-A1 Polynucleotide binding complexes comprising sterols and saponins SNRPE, SNRPF, HNRNPAB ACLY 578/4885ACACA 922/4885EBP 494/4885
US-20040185057-A1 Therapeutical vaccination ICOS, CD69, HAVCR2 ACLY 1657/4885ACACA 2235/4885EBP 4865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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