SCHEMBL2450676

SCHEMBL2450676

CC(C)CCC[C@@H](C)[C@H]1CC(O)[C@@]2(C)[C@@H]3CCC4C(C)(C)CCC[C@@]45CC35CC[C@]12C

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ CDC25A P30304 11/20 0.46
▸ CDC25B P30305 10/20 0.46
▸ EBP Q15125 3/20 0.41
▸ ACLY P53396 2/20 0.39
▸ ACACA Q13085 2/20 0.39
▸ CYP8B1 Q9UNU6 1/20 0.38
▸ NPC1L1 Q9UHC9 1/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ USP2 O75604 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ TP53 P04637 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ INPP5D Q92835 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2450675 1.00 CDC25A (0.46) CDC25ACDC25BEBPACLYACACA
SCHEMBL1050397 0.82 ACLY (0.48) CDC25ACDC25BEBPACLYACACA
SCHEMBL300737 0.82 ACLY (0.48) CDC25ACDC25BEBPACLYACACA
SCHEMBL14116745 0.80 CDC25A (0.51) CDC25ACDC25BEBPACLYACACA
SCHEMBL2453399 0.77 CDC25A (0.40) CDC25ACDC25BEBPNPC1L1
SCHEMBL2453402 0.77 CDC25A (0.40) CDC25ACDC25BEBPNPC1L1
SCHEMBL29934951 0.75 CDC25A (0.59) CDC25ACDC25BEBPACLYACACA
Cycloartanol SCHEMBL1881616 0.71 ACLY (0.67) CDC25ACDC25BEBPACLYACACA
Cycloartanol SCHEMBL13801860 0.71 ACLY (0.67) CDC25ACDC25BEBPACLYACACA
Cycloartanol SCHEMBL12152356 0.71 ACLY (0.67) CDC25ACDC25BEBPACLYACACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013036684-A1 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS SATORI PHARMACEUTICALS, INC (US) 2013-03-14 — — WO disclosed
US-20130060013-A1 Compounds useful for treating neurodegenerative disorders SATORI PHARMACEUTICALS, INC. (US) 2013-03-07 — — US disclosed
EP-2542085-A1 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS Satori Pharmaceuticals, Inc. (US) 2013-01-09 — — EP disclosed
US-20110251379-A1 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS SATORI PHARMACEUTICALS, INC. (US) 2011-10-13 — — US disclosed
WO-2011109657-A1 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS SATORI PHARMACEUTICALS, INC. (US) 2011-09-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130060013-A1 Compounds useful for treating neurodegenerative disorders SNCA, HTT, CLN6 CDC25A 3836/4885CDC25B 4224/4885EBP 784/4885
US-20110251379-A1 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS CLN6, NLN, ACHE CDC25A 4241/4885CDC25B 4330/4885EBP 1228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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