Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.51 |
| ▸ | CASR | P41180 | 5/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10503937 | 0.97 | HTR1A (0.56) | HTR1AADRA2AADRA2BMAOAHTR2B | |
| Fumaric Acid SCHEMBL10505860 | 0.93 | HTR1A (0.51) | HTR1AADRA2AADRA2BMAOAHTR2B | |
| SCHEMBL10503983 | 0.88 | HTR1A (0.55) | HTR1AADRA2AADRA2BMAOAHTR2B | |
| SCHEMBL10592973 | 0.88 | CASR (0.49) | CASRADRB2ADRB3MEN1KMT2A | |
| SCHEMBL10503940 | 0.85 | ADRB2 (0.41) | CASRADRB2ADRB3MEN1KMT2A | |
| SCHEMBL10593339 | 0.85 | ADRB2 (0.47) | HTR1ACYP2D6CASRSLC6A4ADRB2 | |
| SCHEMBL10503702 | 0.85 | CYP2D6 (0.49) | HTR1AADRA2AHTR2BCYP2D6CASR | |
| SCHEMBL10592451 | 0.85 | ADRB2 (0.41) | CASRADRB2ADRB3MEN1KMT2A | |
| SCHEMBL10594657 | 0.85 | CASR (0.43) | HTR1AADRA2AADRA2BMAOAHTR2B | |
| SCHEMBL10592061 | 0.85 | CASR (0.50) | CASRADRB2ADRB3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200915-B1 | AMINOPROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1989-09-27 | — | — | EP | disclosed |
| US-4863949-A | CARDIOVASCULAR DISORDER TREATMENT | BOEHRINGER MANNHEIM GMBH (DE) | 1989-09-05 | — | — | US | disclosed |
| EP-0200915-A1 | Aminopropanol derivatives, process for their preparation, their use and medicines containing them | Roche Diagnostics GmbH (DE) | 1986-11-12 | — | — | EP | disclosed |