Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.52 |
| ▸ | CTSS | P25774 | 3/20 | 0.52 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482895 | 0.89 | CTRB1 (0.57) | CTSLCTSSCTRB1CA12CA1 | |
| SCHEMBL10848448 | 0.84 | CTSL (0.67) | CTSLCTSSCTRB1CA12CA1 | |
| SCHEMBL9383939 | 0.84 | CTSL (0.67) | CTSLCTSSCTRB1CA12CA1 | |
| SCHEMBL10572092 | 0.84 | CTSL (0.67) | CTSLCTSSCTRB1CA12CA1 | |
| SCHEMBL9713340 | 0.84 | CTSL (0.67) | CTSLCTSSCTRB1CA12CA1 | |
| Water SCHEMBL10848660 | 0.83 | CTSS (0.69) | CTSLCTSSECE1CTSBATM | |
| SCHEMBL7305552 | 0.83 | ECE1 (0.64) | CTSLCTSSCA1CA2ECE1 | |
| SCHEMBL13973861 | 0.83 | ECE1 (0.64) | CTSLCTSSCA1CA2ECE1 | |
| SCHEMBL7331078 | 0.83 | ECE1 (0.64) | CTSLCTSSCA1CA2ECE1 | |
| SCHEMBL10504153 | 0.82 | CTSL (0.46) | CTSLCTSSCTRB1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59106444-A | — | — | None | — | — | JP | disclosed |
| EP-0111326-B1 | PROCESS FOR THE MANUFACTURE OF CHIRAL AZETIDINONES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1989-01-11 | — | — | EP | disclosed |
| JP-S59106444-A | PREPARATION OF 4-HYDROXY-L-ALLOTHREONINE AMIDE | TAKEDA CHEM IND LTD | 1984-06-20 | — | — | JP | disclosed |