SCHEMBL1050477

SCHEMBL1050477

CO[Si](OC)(OC)C1CC=CCC1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1703084 0.83
SCHEMBL27971415 0.82
SCHEMBL11073034 0.80 ALDH1A1 (0.31) ALDH1A1ALOX15
SCHEMBL11072482 0.80 ALDH1A1 (0.31) ALDH1A1ALOX15
SCHEMBL11072025 0.78 ALDH1A1 (0.30) ALDH1A1ALOX15
SCHEMBL5831522 0.75
SCHEMBL27709580 0.73
SCHEMBL1052041 0.73 ALDH1A1 (0.36) ALDH1A1ALOX15
SCHEMBL3101133 0.72
SCHEMBL19130371 0.71 MAPK1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629657-B2 Lithium ion adsorbents EMPOWER INNOVATION & TECHNOLOGY LLC (US) 2026-05-19 US claimed
EP-4223409-A1 LITHIUM ION ADSORBENTS Conductive Energy Inc. (CA) 2023-08-09 EP claimed
US-20230241581-A1 LITHIUM ION ADSORBENTS CONDUCTIVE ENERGY INC. (CA) 2023-08-03 US claimed
CN-113663413-B Super-hydrophobic PTFE filter cloth and preparation method thereof 江苏康隆迪超净科技有限公司 2023-03-21 CN claimed
CN-113663413-A Super-hydrophobic PTFE filter cloth and preparation method thereof 江苏康隆迪超净科技有限公司 2021-11-19 CN claimed
US-6465670-B2 SURFACE TREATMENT USING ORGANOSILICON COMPOUND, SOLVENT AND PHASE TRANSFER CATALYST THE GOODYEAR TIRE & RUBBER COMPANY 2002-10-15 US claimed
US-20020022085-A1 Preparation of surface modified silica GOODYEAR TIRE & RUBBER COMPANY, THE 2002-02-21 US claimed
US-12629657-B2 Lithium ion adsorbents EMPOWER INNOVATION & TECHNOLOGY LLC (US) 2026-05-19 US disclosed
US-12371536-B2 Method for preparing a functionalized polyorganosiloxane DOW SILICONES CORPORATION (US) 2025-07-29 US disclosed
US-20240254289-A1 METHOD FOR PREPARING A FUNCTIONALIZED POLYORGANOSILOXANE DOW SILICONES CORPORATION 2024-08-01 US disclosed
EP-4223409-A1 LITHIUM ION ADSORBENTS Conductive Energy Inc. (CA) 2023-08-09 EP disclosed
US-20230241581-A1 LITHIUM ION ADSORBENTS CONDUCTIVE ENERGY INC. (CA) 2023-08-03 US disclosed
EP-3898774-B1 METHOD FOR PREPARING A FUNCTIONALIZED POLYORGANOSILOXANE DOW SILICONES CORP (US) 2023-06-07 EP disclosed
EP-1178077-B1 The preparation of surface modified silica GOODYEAR TIRE & RUBBER (US) 2004-06-16 EP disclosed
US-6465670-B2 SURFACE TREATMENT USING ORGANOSILICON COMPOUND, SOLVENT AND PHASE TRANSFER CATALYST THE GOODYEAR TIRE & RUBBER COMPANY 2002-10-15 US disclosed
US-20020022085-A1 Preparation of surface modified silica GOODYEAR TIRE & RUBBER COMPANY, THE 2002-02-21 US disclosed
EP-1178077-A1 The preparation of surface modified silica THE GOODYEAR TIRE & RUBBER COMPANY (US) 2002-02-06 EP disclosed
EP-0115531-A1 SILOXANE-CONTAINING POLYMERS AND CONTACT LENSES THEREFROM POLYMATIC INVESTMENT CORPORATION N.V. (AN) 1984-08-15 EP disclosed
US-4450264-A CROSSLINKED COPOLYMER OF A TRIS/TRIMETHYLSILOXY/SILYL ALKYL OR CYCLOHEXYL ACRYLATE; OXYGEN PERMEABILITY POLYMATIC INVESTMENT CORP., N.V. (NL) 1984-05-22 US disclosed
WO-1984000763-A1 SILOXANE-CONTAINING POLYMERS AND CONTACT LENSES THEREFROM POLYMATIC INVESTMENT CORP NV (NL) 1984-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629657-B2 Lithium ion adsorbents ILK, SDC1, LAMTOR3 ALDH1A1 2379/4885ALOX15 3412/4885LMNA 353/4885
US-20020022085-A1 Preparation of surface modified silica OSTC, SAMM50, SSRP1 ALDH1A1 3796/4885ALOX15 3728/4885LMNA 690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.