Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8522887 | 0.91 | LIPG (0.38) | ALDH1A1TSHRLIPG | |
| SCHEMBL10534341 | 0.84 | TSHR (0.41) | ALDH1A1TSHRMAPTTAAR1KMT2A | |
| SCHEMBL9625311 | 0.81 | TAAR1 (0.56) | TAAR1MPOHTR2APNMT | |
| SCHEMBL8110497 | 0.81 | TSHR (0.36) | ALDH1A1TSHRTAAR1KMT2ALIPG | |
| SCHEMBL8126752 | 0.81 | PNMT (0.48) | ALDH1A1MAPTCASP3RAB9ANPSR1 | |
| SCHEMBL1446062 | 0.81 | LIPG (0.47) | ALDH1A1TSHRLIPG | |
| SCHEMBL150237 | 0.81 | TSHR (0.50) | ALDH1A1TSHRTAAR1KMT2APNMT | |
| SCHEMBL29350459 | 0.81 | TSHR (0.50) | ALDH1A1TSHRTAAR1KMT2APNMT | |
| Ammonia Solution, Strong SCHEMBL2913066 | 0.79 | LIPG (0.46) | ALDH1A1TSHRLIPG | |
| SCHEMBL8995494 | 0.79 | TSHR (0.35) | ALDH1A1TSHRTAAR1LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142324-B1 | PHENYLALKANOIC ACID DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-01-04 | — | — | EP | disclosed |
| EP-0144695-B1 | IMMUNOGENS, ANTIBODIES, LABELED CONJUGATES, AND RELATED DERIVATIVES FOR LIDOCAINE AND ANALOGS THEREOF | MILES INC. (US) | 1988-06-01 | — | — | EP | disclosed |
| US-4668698-A | [(4-phenyl-1,3-dioxan-cis-5-yl)alkyl]phenylalkanoic acid derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-05-26 | — | — | US | disclosed |
| US-4650771-A | IMMONOASSAY | MILES LABORATORIES, INC. (US) | 1987-03-17 | — | — | US | disclosed |
| US-4647668-A | Disopyramide phenyl derivatives and labeled conjugates | MILES LABORATORIES, INC. (US) | 1987-03-03 | — | — | US | disclosed |
| EP-0095665-B1 | LABELLED CONJUGATES OF ETHOSUXIMIDE, ETHOSUXIMIDE IMMUNOGENS, ANTIBODIES THERETO, IMMUNOASSAY METHOD EMPLOYING THE ANTIBODIES AND REAGENT MEANS, TEST KIT AND TEST DEVICE FOR THE IMMUNOASSAY METHOD | MILES LABORATORIES, INC. (US) | 1986-08-06 | — | — | EP | disclosed |
| EP-0144695-A1 | Immunogens, antibodies, labeled conjugates, and related derivatives for lidocaine and analogs thereof | MILES INC. (US) | 1985-06-19 | — | — | EP | disclosed |
| EP-0142324-A2 | Phenylalkanoic acid derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-05-22 | — | — | EP | disclosed |
| EP-0113100-A2 | Disopyramide immunogens, antibodies, labeled conjugates, and related derivatives | MILES LABORATORIES, INC. (US) | 1984-07-11 | — | — | EP | disclosed |
| EP-0095665-A1 | Labelled conjugates of ethosuximide, ethosuximide immunogens, antibodies thereto, immunoassay method employing the antibodies and reagent means, test kit and test device for the immunoassay method | MILES LABORATORIES, INC. (US) | 1983-12-07 | — | — | EP | disclosed |
| US-4238623-A | 5,6-Benzo analogues of prostaglandin | MILES LABORATORIES, INC. (US) | 1980-12-09 | — | — | US | disclosed |
| US-4100352-A | Cyclohexanone-5,6-benzo analogues of prostaglandin | MILES LABORATORIES, INC. (US) | 1978-07-11 | — | — | US | disclosed |
| US-4100353-A | 5,6-Benza analogues of prostaglandin F | MILES LABORATORIES, INC. (US) | 1978-07-11 | — | — | US | disclosed |
| US-4100185-A | Cyclohexanone 5,6-benzo analogues of prostaglandin E | MILES LABORATORIES, INC. (US) | 1978-07-11 | — | — | US | disclosed |
| US-4097516-A | 5,6-Benzo analogues of prostaglandin E | MILES LABORATORIES, INC. (US) | 1978-06-27 | — | — | US | disclosed |
| US-4097496-A | ANTIPROSTAGLANDIN ACTIVITY | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-06-27 | — | — | US | disclosed |
| US-4096336-A | OXYTOCICS, ANTIULCER, BRONCHODILATION, ANTICOAGULANT, HYPOTENSIVE | MILES LABORATORIES, INC. (US) | 1978-06-20 | — | — | US | disclosed |
| US-4083990-A | ANTIPROSTAGLANDIN EFFECT | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-04-11 | — | — | US | disclosed |
| US-3984459-A | ANTI-PROSTAGLANDINS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-10-05 | — | — | US | disclosed |