Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 10/20 | 0.56 |
| ▸ | HTR2A | P28223 | 4/20 | 0.52 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8126752 | 0.86 | PNMT (0.48) | TAAR1HTR2ASMN1; SMN2LOXL2PNMT | |
| SCHEMBL224549 | 0.83 | TAAR1 (0.70) | TAAR1HTR2AHRH1CYP2A6SMN1; SMN2 | |
| SCHEMBL10505751 | 0.81 | ALDH1A1 (0.39) | TAAR1HTR2AMPOPNMT | |
| SCHEMBL3678681 | 0.78 | TAAR1 (0.50) | TAAR1HTR2AHRH1CYP2A6SMN1; SMN2 | |
| SCHEMBL29943451 | 0.78 | TAAR1 (0.50) | TAAR1HTR2AHRH1CYP2A6SMN1; SMN2 | |
| SCHEMBL7476524 | 0.77 | SIGMAR1 (0.42) | TAAR1SMN1; SMN2CYP1A2CYP3A4PNMT | |
| SCHEMBL31069232 | 0.77 | TAAR1 (0.58) | TAAR1MAOBMPOCYP1A2CYP3A4 | |
| SCHEMBL3067170 | 0.77 | TAAR1 (0.56) | TAAR1HTR2AHRH1CYP3A4CYP2D6 | |
| SCHEMBL3520428 | 0.77 | TAAR1 (0.58) | TAAR1MAOBMPOCYP1A2CYP3A4 | |
| SCHEMBL6314758 | 0.75 | HTR2A (0.74) | TAAR1HTR2AHRH1CYP2A6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0329010-B1 | NOREMOPAMIL, ITS PREPARATION AND ITS USE | BASF Aktiengesellschaft (DE) | 1992-05-06 | — | — | EP | disclosed |
| EP-0329010-A1 | Noremopamil, its preparation and its use | BASF Aktiengesellschaft (DE) | 1989-08-23 | — | — | EP | disclosed |