Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 4/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL1050654 | 0.90 | BBOX1 (0.43) | BBOX1FFAR3HDAC3HDAC1HDAC2 | |
| Bicarbonate SCHEMBL31088022 | 0.90 | BBOX1 (0.43) | BBOX1FFAR3HDAC3HDAC1HDAC2 | |
| Oxalic Acid SCHEMBL1050655 | 0.87 | ALOX15 (0.37) | BBOX1FFAR3HDAC3HDAC1HDAC2 | |
| Tributylmethylammonium SCHEMBL1052295 | 0.86 | BBOX1 (0.47) | BBOX1CES2CES1TSHRCA1 | |
| Acetic Acid SCHEMBL557807 | 0.84 | CA1 (0.44) | BBOX1FFAR3HDAC3HDAC1HDAC2 | |
| Oxalic Acid SCHEMBL7624961 | 0.82 | LSS (0.46) | BBOX1CES2CES1 | |
| Propionic Acid SCHEMBL5571744 | 0.82 | BBOX1 (0.46) | BBOX1FFAR3HDAC3HDAC1HDAC2 | |
| Tetrapropylammonium SCHEMBL107313 | 0.82 | SLC22A1 (0.53) | BBOX1FFAR3HDAC3HDAC1HDAC2 | |
| Fumaric Acid SCHEMBL4929679 | 0.81 | BBOX1 (0.45) | BBOX1FFAR3HDAC3HDAC1HDAC2 | |
| Fumaric Acid SCHEMBL4929346 | 0.81 | BBOX1 (0.45) | BBOX1FFAR3HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7867471-B2 | Process for preparing advanced ceramic powders using onium dicarboxylates | SACHEM, INC. (US) | 2011-01-11 | — | — | US | disclosed |
| US-20090250850-A1 | PROCESS FOR PREPARING ADVANCED CERAMIC POWDERS USING ONIUM DICARBOXYLATES | SACHEM, INC. | 2009-10-08 | — | — | US | disclosed |