Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 15/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | TOP2A | P11388 | 2/20 | 0.60 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.60 |
| ▸ | HTR1D | P28221 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5476725 | 0.88 | NISCH (0.79) | NISCHLMNARECQLTOP2ATOP2B | |
| SCHEMBL105024 | 0.82 | NISCH (1.00) | NISCHLMNARECQLTOP2ATOP2B | |
| Ammonia Solution, Strong SCHEMBL7104964 | 0.80 | NISCH (0.96) | NISCHLMNARECQLTOP2ATOP2B | |
| SCHEMBL533283 | 0.80 | NISCH (0.67) | NISCHLMNARECQLTOP2ATOP2B | |
| SCHEMBL28772851 | 0.80 | NISCH (0.96) | NISCHLMNARECQLTOP2ATOP2B | |
| Bromide SCHEMBL29039569 | 0.80 | NISCH (0.96) | NISCHLMNARECQLTOP2ATOP2B | |
| SCHEMBL2518908 | 0.78 | NISCH (0.66) | NISCHLMNARECQLTOP2ATOP2B | |
| SCHEMBL8141372 | 0.78 | NISCH (1.00) | NISCHLMNARECQLTOP2ATOP2B | |
| SCHEMBL771337 | 0.78 | NISCH (0.66) | NISCHLMNARECQLTOP2ATOP2B | |
| SCHEMBL17826831 | 0.78 | NISCH (0.66) | NISCHLMNARECQLTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4246394-A | PROMOTER FOR CROSSLINKING | VEBA-CHEMIE AKTIENGESELLSCHAFT (DE) | 1981-01-20 | — | — | US | claimed |
| EP-0159011-B1 | CEPHALOSPORIN DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DAIICHI SEIYAKU CO., LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |
| US-4833242-A | ANTIBIOTICS, BACTERICIDES | DAIICHI SEIYAKU CO., LTD. (JP) | 1989-05-23 | — | — | US | disclosed |
| US-4605744-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1986-08-12 | — | — | US | disclosed |
| EP-0159011-A2 | Cephalosporin derivatives, process for preparing them and pharmaceutical compositions containing them | DAIICHI SEIYAKU CO., LTD. (JP) | 1985-10-23 | — | — | EP | disclosed |
| US-4537969-A | AZOLE-SUBSTITUTED SATURATED HETEROCYCLIC CARBOXALDEHYDE ACETALS;INTERMEDIATES FOR 6-AMIDINOPENICILLINS | HOFFMANN-LA ROCHE INC. (US) | 1985-08-27 | — | — | US | disclosed |
| EP-0148283-A1 | Novel penicillanic acid derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-07-17 | — | — | EP | disclosed |
| US-4431653-A | ANTIBIOTICS; BACTERICIDES; SSYNERGISTIC WITH AMINO ACID DERIVATIVE | HOFFMANN-LA ROCHE INC. (US) | 1984-02-14 | — | — | US | disclosed |
| US-4246394-A | PROMOTER FOR CROSSLINKING | VEBA-CHEMIE AKTIENGESELLSCHAFT (DE) | 1981-01-20 | — | — | US | disclosed |