Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 12/20 | 0.96 |
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | CASP1 | P29466 | 1/20 | 0.71 |
| ▸ | CASP7 | P55210 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | TOP2A | P11388 | 1/20 | 0.58 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL105024 | 0.98 | NISCH (1.00) | NISCHGAATSHRALDH1A1CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL7104964 | 0.96 | NISCH (0.96) | NISCHGAATSHRALDH1A1CYP1A2 | |
| SCHEMBL28772851 | 0.96 | NISCH (0.96) | NISCHGAATSHRALDH1A1CYP1A2 | |
| SCHEMBL8141372 | 0.94 | NISCH (1.00) | NISCHGAATSHRALDH1A1CYP1A2 | |
| SCHEMBL28515381 | 0.90 | NISCH (0.85) | NISCHGAATSHRALDH1A1CYP1A2 | |
| Alcohol SCHEMBL28563093 | 0.87 | NISCH (0.79) | NISCHGAATSHRALDH1A1CYP1A2 | |
| SCHEMBL5476725 | 0.86 | NISCH (0.79) | NISCHALDH1A1CYP1A2HPGDCASP1 | |
| SCHEMBL28215309 | 0.85 | NISCH (0.76) | NISCHGAATSHRALDH1A1CYP1A2 | |
| SCHEMBL6365864 | 0.85 | NISCH (1.00) | NISCHGAATSHRALDH1A1CYP1A2 | |
| SCHEMBL24495491 | 0.84 | NISCH (1.00) | NISCHGAATSHRALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108787388-B | Production process and production equipment for forming mirror surface high-gloss decorative effect on surface of artificial board by using powder coating | 佛山宜可居新材料有限公司 | 2023-10-10 | — | — | CN | claimed |
| CN-108787378-B | Equipment and method for curing powder coating on surface of artificial board | 佛山宜可居新材料有限公司 | 2023-07-28 | — | — | CN | claimed |
| CN-108787388-B | Production process and production equipment for forming mirror surface high-gloss decorative effect on surface of artificial board by using powder coating | 佛山宜可居新材料有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-108787378-B | Equipment and method for curing powder coating on surface of artificial board | 佛山宜可居新材料有限公司 | 2023-07-28 | — | — | CN | disclosed |