Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7104964

N.c1ccc(C2=NCCN2)cc1

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 12/20 0.96
GAA P10253 1/20 0.74
TSHR P16473 1/20 0.74
ALDH1A1 P00352 1/20 0.71
CYP1A2 P05177 1/20 0.71
HPGD P15428 1/20 0.71
CASP1 P29466 1/20 0.71
CASP7 P55210 1/20 0.71
HSD17B10 Q99714 1/20 0.71
LMNA P02545 1/20 0.60
RECQL P46063 1/20 0.60
MAOB P27338 1/20 0.59
TOP2A P11388 1/20 0.58
TOP2B Q02880 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL105024 0.98 NISCH (1.00) NISCHGAATSHRALDH1A1CYP1A2
SCHEMBL28772851 0.96 NISCH (0.96) NISCHGAATSHRALDH1A1CYP1A2
Bromide SCHEMBL29039569 0.96 NISCH (0.96) NISCHGAATSHRALDH1A1CYP1A2
SCHEMBL8141372 0.94 NISCH (1.00) NISCHGAATSHRALDH1A1CYP1A2
SCHEMBL28515381 0.90 NISCH (0.85) NISCHGAATSHRALDH1A1CYP1A2
Alcohol SCHEMBL28563093 0.87 NISCH (0.79) NISCHGAATSHRALDH1A1CYP1A2
SCHEMBL5476725 0.86 NISCH (0.79) NISCHALDH1A1CYP1A2HPGDCASP1
SCHEMBL28215309 0.85 NISCH (0.76) NISCHGAATSHRALDH1A1CYP1A2
SCHEMBL6365864 0.85 NISCH (1.00) NISCHGAATSHRALDH1A1CYP1A2
SCHEMBL24495491 0.84 NISCH (1.00) NISCHGAATSHRALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1176175-A2 Matte texture powder coatings ROHM AND HAAS COMPANY (US) 2002-01-30 EP claimed
EP-1176175-A3 Matte texture powder coatings ROHM AND HAAS COMPANY (US) 2003-09-24 EP disclosed
US-6432488-B1 POWDER COATING ROHM AND HAAS COMPANY 2002-08-13 US disclosed
EP-1176175-A2 Matte texture powder coatings ROHM AND HAAS COMPANY (US) 2002-01-30 EP disclosed