SCHEMBL1050751

SCHEMBL1050751

Nc1c(Br)cc(C(F)(C(F)(F)F)C(F)(F)F)cc1C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 9/20 0.39
GAA P10253 2/20 0.34
MAPT P10636 1/20 0.34
GLA P06280 1/20 0.32
POLB P06746 1/20 0.32
TSHR P16473 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18726209 0.92 ADRB2 (0.37) ADRB2GAAMAPTGLAPOLB
SCHEMBL999095 0.91 ADRB2 (0.36) ADRB2GAAMAPT
SCHEMBL1767353 0.89 GAA (0.32) ADRB2GAAMAPT
SCHEMBL1274565 0.87 GAA (0.46) GAAMAPTCA1CA2CA9
SCHEMBL1766862 0.84 ADRB2 (0.39) ADRB2GAAMAPTGLAPOLB
SCHEMBL20537245 0.83 TSHR (0.34) GAAMAPTGLAPOLBTSHR
SCHEMBL21701241 0.80 NOTUM (0.34)
SCHEMBL9894480 0.80 POLB (0.39) GAAMAPTPOLBTSHRALDH1A1
SCHEMBL12440998 0.80 POLB (0.39) GAAGLAPOLBTSHRALDH1A1
SCHEMBL16155869 0.79 GAA (0.42) GAAMAPTCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119059926-A Synthetic process method of pesticide bromofluorobenzene bisamide 天津均凯农业科技有限公司 2024-12-03 CN claimed
CN-117430518-A Synthesis method of chlorantraniliprole and pesticide 利民化学有限责任公司 2024-01-23 CN claimed
CN-120717904-A Method for synthesizing bromofluorobenzene bisamide intermediate by one-pot method 湖南速博生物技术有限公司 2025-09-30 CN disclosed
CN-120208792-A Preparation process of 2-bromo-4- (perfluoropropane-2-yl) -6- (trifluoromethyl) aniline 大愿健康管理(山东)集团有限公司 2025-06-27 CN disclosed
CN-120208792-A Preparation process of 2-bromo-4- (perfluoropropane-2-yl) -6- (trifluoromethyl) aniline 大愿健康管理(山东)集团有限公司 2025-06-27 CN disclosed
CN-115611767-B Amide compound and application thereof 沈阳化工大学 2025-03-25 CN disclosed
CN-119569605-A Amide compound and application thereof 沈阳化工大学 2025-03-07 CN disclosed
CN-118724864-B Amide derivative and application thereof 山东诚创蓝海医药科技有限公司 2025-01-28 CN disclosed
CN-119219519-A Amide compound and application thereof 沈阳化工大学 2024-12-31 CN disclosed
CN-119143667-A Amide compound and application thereof 沈阳化工大学 2024-12-17 CN disclosed
CN-119059926-A Synthetic process method of pesticide bromofluorobenzene bisamide 天津均凯农业科技有限公司 2024-12-03 CN disclosed
US-20110137068-A1 METHOD FOR PRODUCING AMIDE DERIVATIVE MITSUI CHEMICALS AGRO, INC. (JP) 2011-06-09 US disclosed
US-20110136878-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD Mitsui Chemicals Agro., Inc. (JP) 2011-06-09 US disclosed
US-20110136878-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD Mitsui Chemicals Agro., Inc. (JP) 2011-06-09 US disclosed
US-20110136878-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD Mitsui Chemicals Agro., Inc. (JP) 2011-06-09 US disclosed
EP-2325165-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND PEST CONTROLLING METHOD Mitsui Chemicals Agro, Inc. (JP) 2011-05-25 EP disclosed
EP-2322502-A1 METHOD FOR PRODUCING AMIDE DERIVATIVE Mitsui Chemicals Agro, Inc. (JP) 2011-05-18 EP disclosed
EP-2319830-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND USE OF THE PEST CONTROL AGENT Mitsui Chemicals Agro, Inc. (JP) 2011-05-11 EP disclosed
WO-2011018170-A2 PESTICIDAL CARBOXAMIDES BAYER CROPSCIENCE AG (DE) 2011-02-17 WO disclosed
WO-2011009540-A2 PESTICIDAL CARBOXAMIDES BAYER CROPSCIENCE AG (DE) 2011-01-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110136878-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD L3MBTL1, L3MBTL4, L3MBTL3 ADRB2 4047/4885GAA 3220/4885MAPT 4155/4885
US-20110137068-A1 METHOD FOR PRODUCING AMIDE DERIVATIVE AFF4, AFF1, AFF2 ADRB2 1890/4885GAA 4501/4885MAPT 4569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.