Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10507609 | 0.85 | GAA (0.49) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8973886 | 0.84 | ALDH1A1 (0.58) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9808915 | 0.84 | PDGFRB (0.53) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10507595 | 0.79 | ALDH1A1 (0.51) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9808912 | 0.75 | LMNA (0.54) | MAPTALDH1A1LMNAGAAPOLB | |
| SCHEMBL3994737 | 0.74 | MAPT (0.64) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL1984504 | 0.74 | ALDH1A1 (0.56) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29151237 | 0.74 | ALDH1A1 (0.72) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2611830 | 0.74 | ALDH1A1 (0.61) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL30753688 | 0.74 | MAPT (0.64) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4831194-A | Process for the preparation of nitrodiaryl sulfoxides | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-05-16 | — | — | US | disclosed |
| US-4710323-A | Nitrodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them as active ingredient | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-12-01 | — | — | US | disclosed |