Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.46 |
| ▸ | TUBB | P07437 | 3/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10507601 | 0.84 | MAPT (0.49) | PDGFRBPDGFRAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL9808919 | 0.84 | ALDH1A1 (0.54) | PDGFRBPDGFRAALDH1A1TDP1TUBB4A | |
| SCHEMBL28546991 | 0.83 | PDGFRB (0.57) | PDGFRBPDGFRAALDH1A1TDP1TUBB4A | |
| SCHEMBL12312144 | 0.83 | PDGFRB (0.57) | PDGFRBPDGFRAALDH1A1TDP1TUBB4A | |
| SCHEMBL7562427 | 0.83 | ALDH1A1 (0.61) | PDGFRBPDGFRAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL12312167 | 0.80 | KMT2A (0.58) | PDGFRBPDGFRAALDH1A1TDP1TUBB4A | |
| SCHEMBL18830795 | 0.78 | ALDH1A1 (0.50) | PDGFRBPDGFRAALDH1A1TDP1TUBB4A | |
| SCHEMBL27703189 | 0.78 | ALDH1A1 (0.50) | PDGFRBPDGFRAALDH1A1TDP1TUBB4A | |
| SCHEMBL9808911 | 0.77 | ALDH1A1 (0.50) | PDGFRBPDGFRAALDH1A1TDP1TUBB4A | |
| SCHEMBL4623856 | 0.77 | ALDH1A1 (0.57) | PDGFRBPDGFRAALDH1A1TDP1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985463-A | Aminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-01-15 | — | — | US | disclosed |
| US-4831194-A | Process for the preparation of nitrodiaryl sulfoxides | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-05-16 | — | — | US | disclosed |
| US-4710323-A | Nitrodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them as active ingredient | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-12-01 | — | — | US | disclosed |