Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808916 | 0.85 | HCAR3 (0.56) | LMNAHCAR3GAAMAPTALDH1A1 | |
| SCHEMBL9808908 | 0.79 | LMNA (0.50) | LMNAHCAR3GAAMAPTABCB1 | |
| SCHEMBL9808939 | 0.77 | KDM4E (0.45) | LMNAGAAMAPTABCB1ALDH1A1 | |
| SCHEMBL10507601 | 0.75 | MAPT (0.49) | LMNAGAAMAPTALDH1A1HTT | |
| SCHEMBL27471431 | 0.75 | MAPT (0.64) | LMNAHCAR3GAAMAPTALDH1A1 | |
| SCHEMBL5981763 | 0.74 | HCAR3 (0.63) | LMNAHCAR3GAAMAPTALDH1A1 | |
| SCHEMBL6250970 | 0.74 | KAT2B (0.66) | LMNAHCAR3MAPTALDH1A1HTT | |
| SCHEMBL30169708 | 0.74 | HCAR3 (0.63) | LMNAHCAR3GAAMAPTALDH1A1 | |
| SCHEMBL5149985 | 0.73 | ALDH1A1 (0.67) | LMNAHCAR3MAPTALDH1A1HTT | |
| SCHEMBL4428318 | 0.73 | HCAR3 (0.61) | LMNAHCAR3GAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985463-A | Aminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-01-15 | — | — | US | disclosed |
| US-4956007-A | Nitraminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYOR RT. (HU) | 1990-09-11 | — | — | US | disclosed |
| US-4831194-A | Process for the preparation of nitrodiaryl sulfoxides | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-05-16 | — | — | US | disclosed |
| US-4710323-A | Nitrodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them as active ingredient | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-12-01 | — | — | US | disclosed |