Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10512041 | 0.96 | SLC6A3 (0.46) | ALDH1A1HSD17B10CFTRSLC6A3SLC6A2 | |
| SCHEMBL27770641 | 0.85 | SLC6A3 (0.41) | ALDH1A1SLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL27770700 | 0.85 | KMT2A (0.51) | SLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL11203722 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HSD17B10CFTRHPGDTSHR | |
| SCHEMBL3065287 | 0.76 | KMT2A (0.44) | ALDH1A1SLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL8803961 | 0.74 | SLC6A3 (0.48) | ALDH1A1SLC6A3 | |
| SCHEMBL3058944 | 0.72 | ALDH1A1 (0.48) | ALDH1A1HSD17B10POLBLMNA | |
| SCHEMBL11717919 | 0.72 | SLC6A3 (0.38) | ALDH1A1SLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL8801807 | 0.72 | GAA (0.52) | — | |
| SCHEMBL3507300 | 0.72 | ALDH1A1 (0.63) | ALDH1A1HSD17B10CFTRHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094065-B1 | 2-AMINOBENZOIC ACID DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | FERRER INTERNACIONAL, S.A. (ES) | 1989-12-20 | — | — | EP | disclosed |