Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27770700 | 0.85 | KMT2A (0.51) | SLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL10508162 | 0.85 | ALDH1A1 (0.44) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL10512041 | 0.81 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL3065287 | 0.76 | KMT2A (0.44) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL3058944 | 0.72 | ALDH1A1 (0.48) | ALDH1A1LMNA | |
| SCHEMBL14231067 | 0.72 | ELANE (0.46) | ALDH1A1TSHR | |
| SCHEMBL14230971 | 0.72 | ELANE (0.46) | ALDH1A1TSHR | |
| SCHEMBL1873958 | 0.72 | SLC6A3 (0.44) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL1878142 | 0.72 | SLC6A3 (0.44) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL7059883 | 0.71 | FAAH (0.53) | SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101622258-B | Bicyclic oxomorpholine derivatives | EISAI R&D MAN CO LTD | 2012-06-13 | — | — | CN | disclosed |
| CN-101622258-A | Bicyclic oxomorpholine derivatives | EISAI R&D MAN CO LTD | 2010-01-06 | — | — | CN | disclosed |