Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803961 | 0.83 | SLC6A3 (0.48) | HTR4ACHE | |
| SCHEMBL8803576 | 0.78 | HTR4 (0.54) | HTR4 | |
| SCHEMBL10512041 | 0.76 | SLC6A3 (0.46) | — | |
| SCHEMBL10721778 | 0.76 | HTR4 (0.56) | HTR4 | |
| SCHEMBL9406887 | 0.74 | HTR4 (0.54) | HTR4 | |
| SCHEMBL27770700 | 0.72 | KMT2A (0.51) | — | |
| SCHEMBL10508162 | 0.72 | ALDH1A1 (0.44) | — | |
| SCHEMBL9342410 | 0.72 | HTR4 (0.47) | GAAHTR4 | |
| SCHEMBL1502421 | 0.72 | HTR4 (0.67) | HTR4 | |
| SCHEMBL384749 | 0.70 | GAA (1.00) | GAAHTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499995-B1 | Piperidine derivatives | NISSHIN FLOUR MILLING CO (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5246945-A | 5-hydroxytryptamine antagonist for nervous system disorders | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0499995-A2 | Piperidine derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-08-26 | — | — | EP | disclosed |