Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10509418 | 1.00 | GRM7 (0.47) | GRM7MEN1KMT2ANPC1RAB9A | |
| SCHEMBL30777029 | 0.86 | GRM7 (0.49) | GRM7KDM4EALDH1A1L3MBTL1SLC11A2 | |
| SCHEMBL10511120 | 0.86 | MEN1 (0.40) | GRM7MEN1KMT2ANPC1RAB9A | |
| SCHEMBL29175817 | 0.86 | GRM7 (0.49) | GRM7KDM4EALDH1A1L3MBTL1SLC11A2 | |
| SCHEMBL10511107 | 0.86 | MEN1 (0.40) | GRM7MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10507488 | 0.84 | NPBWR1 (0.51) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL10507500 | 0.84 | NPBWR1 (0.51) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL10508337 | 0.83 | SMN1; SMN2 (0.50) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL10508351 | 0.83 | SMN1; SMN2 (0.50) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL10509004 | 0.81 | NPBWR1 (0.50) | KMT2ANPC1RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0164593-B1 | ANTI-INFLAMMATORY PHTHALAZINONES | FISONS CORPORATION (US) | 1989-11-15 | — | — | EP | disclosed |
| US-4665181-A | Anti-inflammatory phthalazinones | PENNWALT CORPORATION (US) | 1987-05-12 | — | — | US | disclosed |
| EP-0164593-A1 | Anti-inflammatory phthalazinones | FISONS CORPORATION (US) | 1985-12-18 | — | — | EP | disclosed |