Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | NPBWR1 | P48145 | 8/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10508351 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL10509051 | 0.94 | NPBWR1 (0.53) | SMN1; SMN2KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL10509058 | 0.94 | NPBWR1 (0.53) | SMN1; SMN2KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL10507488 | 0.94 | NPBWR1 (0.51) | SMN1; SMN2KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL10507500 | 0.94 | NPBWR1 (0.51) | SMN1; SMN2KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL10510131 | 0.90 | PTGS2 (0.49) | SMN1; SMN2KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL10510119 | 0.90 | PTGS2 (0.49) | SMN1; SMN2KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL10509004 | 0.83 | NPBWR1 (0.50) | SMN1; SMN2KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL10509418 | 0.83 | GRM7 (0.47) | KMT2AALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL10509429 | 0.83 | GRM7 (0.47) | KMT2AALDH1A1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0164593-B1 | ANTI-INFLAMMATORY PHTHALAZINONES | FISONS CORPORATION (US) | 1989-11-15 | — | — | EP | disclosed |
| US-4665181-A | Anti-inflammatory phthalazinones | PENNWALT CORPORATION (US) | 1987-05-12 | — | — | US | disclosed |
| EP-0164593-A1 | Anti-inflammatory phthalazinones | FISONS CORPORATION (US) | 1985-12-18 | — | — | EP | disclosed |