SCHEMBL10509802

SCHEMBL10509802

COc1nc(N=C=S)nc(OC)n1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.35
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
MIF P14174 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10395131 0.88 GAA (0.34) APLNR
SCHEMBL9877006 0.74 L3MBTL1 (0.47) APLNRALDH1A1MIF
SCHEMBL3666992 0.74 ALDH1A1 (0.34) APLNRALDH1A1
SCHEMBL5026448 0.72 ALDH1A1 (0.33) ALDH1A1MEN1KMT2A
SCHEMBL5026444 0.72 ALDH1A1 (0.33) ALDH1A1MEN1KMT2A
SCHEMBL33145 0.71 ALDH1A1 (0.43) ALDH1A1MEN1KMT2A
SCHEMBL10395196 0.69
SCHEMBL13026224 0.67 GAA (0.34) ALDH1A1
SCHEMBL10394994 0.65 POLB (0.37) ALDH1A1MEN1KMT2AMIF
SCHEMBL11286274 0.65 HTR2C (0.39) APLNRALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4830662-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-05-16 US disclosed
US-4818278-A N-/HETEROCYCLICAMINOCARBONYL/ARYL SULFONAMIDES; HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-04-04 US disclosed
US-4776878-A PLANT GROWTH REGULATORS OR HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-10-11 US disclosed
US-4755216-A Herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-07-05 US disclosed
US-4721520-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-01-26 US disclosed
US-4689072-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-08-25 US disclosed
US-4687507-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-08-18 US disclosed
US-4647303-A Agriculture sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-03-03 US disclosed
US-4627873-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-12-09 US disclosed
US-4592978-A Herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-06-03 US disclosed
US-4383113-A PLANT GROWTH REGULATORS, HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-05-10 US disclosed
EP-0013480-B1 HERBICIDAL PYRIDINESULFONAMIDES, PREPARATION AND USE THEREOF AND COMPOSITIONS CONTAINING THEM E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-03-16 EP disclosed
US-4348219-A PREEMERGENCE AND POSTEMERGENCE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-09-07 US disclosed
EP-0044209-A1 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-01-20 EP disclosed
US-4310346-A HERBICIDES AND PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-01-12 US disclosed
EP-0030138-A1 Herbicidal sulfonamides, and compositions, preparation and use thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-10 EP disclosed
EP-0023422-A2 Herbicidal sulfonamides, preparation and use thereof, and compositions containing them E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-02-04 EP disclosed
EP-0023141-A2 Herbicidal sulfonamides, preparation and use thereof, compositions containing them, intermediates therefor and preparation of such intermediates E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-01-28 EP disclosed
EP-0013480-A2 Herbicidal pyridinesulfonamides, preparation and use thereof and compositions containing them E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-07-23 EP disclosed
EP-0007687-A1 Sulfonamides, processes for their preparation, compositions containing said sulfonamides and a method for controlling the growth of vegetation E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-02-06 EP disclosed